Emerging studies suggest the gut microbiome may predict how well you age. The world’s oldest person offers scientists new clues into the secrets of healthy aging and protection against the diseases that often plague the final years of life.
After two decades of scientific exploration, the human microbiome has emerged as a critical determinant of health and disease. Fueled by multi-omics technologies and machine learning, the field has advanced from correlation-based observations to establishing causal relationships. This article presents recent and compelling examples of microbiome-based treatments that are ripe for clinical adoption and discusses challenges and opportunities facing the field based on expert interviews conducted by the GMFH team.
Best practices for designing better clinical trials of probiotics and prebiotics
27 Mar 2025by Andreu Prados
Diet can impact the efficacy of prebiotics and probiotics. A new perspective article in Nature Microbiology makes 10 recommendations for designing, conducting, and reporting clinical trials of prebiotics and probiotics that support best practices in microbiome research.
The gut, its microbiota, and the liver communicate through complex interactions. This communication, known as the gut-liver axis, plays a crucial role in maintaining liver health and preventing disease. We will explore the role of gut microbiota in the gut-liver axis and delve into the emerging microbiota-based therapies that hold promise for liver diseases.
Scientists are starting to elucidate the roots of gastrointestinal symptoms that appear after a meal in people with irritable bowel syndrome. Current research highlights the immune drivers of gut pain, which could offer clues on how to treat IBS.
What you need to know about the effects of antibiotics on the gut microbiome and how to recover after taking them
18 Sep 2024by Andreu Prados
While antibiotics save countless lives each year, they can cause irreversible changes to the balance of the gut ecosystem. Learn more about the short- and long-term effects of antibiotics on gut health, as well as science-based strategies for recovery after their use.
Dysosmobacter welbionis as potential promising next-generation probiotic for improving metabolic health?
8 May 2024by Patrice D. Cani
Dysosmobacter welbionis is a typical inhabitant of the human gut. New findings suggest it could be a potential next-generation beneficial bacterium for tackling specific cardiometabolic disorders linked to obesity and type 2 diabetes.
Fermented foods like yogurt, kefir, and sauerkraut are dietary staples for many cultures worldwide. Now scientists understand better how eating these foods as part of a balanced diet may contribute to improving gut health.
Patients with metabolic liver diseases may benefit from supplements of a common gut bacterium, a small study suggests.
Differences in the gut microbiota in patients with IBD compared to healthy controls suggest that probiotics may be of help. This article takes an in-depth look into the rationale of using probiotics for IBD and summarizes the evidence from recent clinical guidelines for the use of probiotics in Crohn’s disease, ulcerative colitis and pouchitis.
