Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.
by Andreu Prados
While “gut health” is becoming a popular term, mainly in media and marketing claims but also in the clinical context, researchers have not yet nailed down a definition. Now, a global group of 13 scientists and clinicians updates a consensus definition of gut health and implications from bench to bedside.
The management of disorders of gut-brain interaction based on their causes was a central topic addressed at NeuroGASTRO 2025. In this video interview, Dr. Javier Santos delves into the role of mast cells in postprandial symptoms and the present and future of microbiome-based interventions for bowel disorders.
by Manon Oliero
Much of nutrition science has centred on what we put on our plate, yet when we choose to eat may be just as consequential. Intermittent fasting (IF) has gained attention as a strategy that may support metabolic health while also reshaping microbial rhythms, gut hormone secretion, and intestinal function. The growing interest surrounding this approach raises an essential question for clinical practice: does IF truly translate into measurable benefits?
by GMFH Editing Team
Gut microbiome-related interventions for the management of disorders of gut-brain interaction were on the agenda of NeuroGASTRO 2025. In this video interview, Dr. Juan M. Mendive delves into the role of the gut microbiome for improving outcomes of primary care patients with IBS.
by Andreu Prados
Chronic constipation affects around one in ten adults worldwide. The new British Dietetic Association’s guidelines show that psyllium, certain probiotic strains and magnesium oxide supplements can help to improve constipation.
by Nathalie Rolhion, Harry Sokol
Antibiotic treatments can profoundly disrupt gut microbiome structure and function. This article reviews new findings showing how Saccharomyces boulardii CNCM I-745 helps preserve microbial activity and metabolic resilience during antibiotic stress, with insights from advanced in vitro models and immune assays.
2025 has been a productive year in gut microbiome research, spanning metabolic health, neurogastroenterology, immune modulation, and precision nutrition. In this ‘Year in Review’ article, the GMFH editing team describes their pick of the top GMFH-covered advances in 2025, outlining their impact in the clinical setting and implications for current and future research.
by Mónica Quinzo
The definition of a prebiotic has evolved from a focus on colonic fiber to a complex ecological strategy. This article traces the concept's 30-year journey, highlighting the shift from non-digestible carbohydrates to the latest expert recommendations.
by Andreu Prados
Cardiovascular diseases remain one of the most pressing public health concerns, demanding innovative research to identify novel causes. A recent Nature study reported that imidazole propionate made by gut bacteria contributes to atherosclerosis development, supporting its potential role as a biomarker of subclinical disease.
by Karen Madsen
Previous clinical studies have shown a promising role of fecal microbiota transplantation to induce remission in ulcerative colitis and maintain steroid-induced Crohn’s disease remission. A new double-blind, placebo-controlled trial found fecal microbiota transplantation is not effective at inducing clinical or endoscopic remission in adults with Crohn’s disease.
