Diet is one of the cornerstones for managing IBS. The study of mechanisms of action coupled with symptom-related data are valuable for understanding the role of exclusion diets in patients with IBS.
Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.
Meal ingestion usually induces a wealth of sensations before, during and afterwards. A new brain imaging study reveals sex-specific differences in subjective responses to a palatable meal at thalamic and insular connectivity level in healthy individuals.
Nomadic Irish Travellers’ gut microbiome is shaped by housing conditions rather than diet and can be seen as an indicator of cultural transition
20 Jul 2020by Andreu Prados
From hunter-gathering to agriculture and industrialization, the gut microbiome has evolved under diet and lifestyle pressures. An Ireland-based team finds that housing conditions are a major factor within the Irish Traveller ethnic minority, determining both gut microbiome make-up and its link with metabolic diseases.
An altered gut microbiota in mothers with IBD can be transferred to their offspring and involves changes in mucosal adaptive immune responses
13 Jul 2020by GMFH Editing Team
How pregnancy can impact an offspring’s gut microbiota is unknown. New research reveals that children born to mothers with IBD present an altered gut microbiota composition and lower diversity, transferring abnormalities in the adaptive immune system to germ-free mice.
Fungi are not universally present in human milk and are shaped by early life factors and the outdoor environment
6 Jul 2020by Andreu Prados
Bacteria in human milk play an important role in kick-starting the colonization of an infant’s gut. Researchers are looking at how perinatal and environmental factors may shape the overlooked fungi in breast milk.
Challenges and next steps in using human fecal microbiota transfer to germ-free mice models as a means of translating microbiome science to therapeutic medicine
2 Jul 2020by Rene van den Wijngaard
Human microbiota-associated mice studies are considered a cornerstone model in microbiome research and may contribute to microbiome-based therapies moving quickly towards clinical use. A new perspective from Jens Walter and colleagues explores the model’s limitations and makes suggestions for improving experimental rigor when testing for causality in microbiome research.
It is largely recognized that a high-salt diet can lead to hypertension. A new randomized controlled trial reports that, particularly in females with untreated hypertension, reducing salt intake to recommended levels is linked to decreased blood pressure, more compliant blood vessels and increased serum levels of short-chain fatty acids.
New research shows the keto diet, used to treat neurological and metabolic diseases, suppresses bifidobacteria and Th17 cells
15 Jun 2020by Andreu Prados
Could the keto diet’s therapeutic benefits be linked to changes in the gut microbiota? New work in mice and 17 men who are overweight or obese reveals ketone bodies exert suppression of bifidobacteria and intestinal pro-inflammatory Th17 cells.
Lactic acid bacteria in fermented foods can be transferred to the human gut
8 Jun 2020by GMFH Editing Team
Fermented foods are a known source of lactic acid bacteria. A high-throughput sequencing analysis of food and human metagenomes proves that fermented foods are a source of lactic acid bacteria for the gut microbiome, and that abundance is shaped by both age and lifestyle.
Gut microbiota alterations in obesity remain the subject of debate. Writing in Nature, Vieira-Silva and colleagues found that the undesirable Bacteroides 2 enterotype was more frequent in people with a higher body mass index, but not if they were taking statins.