Archives des Research & Practice

Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.

What are the factors that predict complications associated with Clostridioides difficile infection and what can be done in clinical practice?

21 Nov 2022

by Andreu Prados

Clostridioides difficile infection is a common cause of diarrhea in both the hospital and community settings, with C. difficile recurrence one of the most challenging outcomes to address. This article focuses on the factors that predict long-term complications of C. difficile infection and what can be done in clinical practice to minimize them (Part 5).

November, Clostridioides difficile infection awareness month

11 Nov 2022

by Konstantina Zafeiropoulou

Just one month before friends and families gather around the Christmas table, November is here to bring awareness around Clostridioides difficile infection, and the importance of microbiota-derived treatments. With this post, all of us in GMFH aim to highlight the importance of protecting ourselves and families and stopping the spread of this potentially deadly infection.

Bacterial extracellular vesicles: future postbiotics?

18 Oct 2022

by Konstantina Zafeiropoulou

Research into microbial extracellular vesicles has progressed significantly over several decades. Following up on the 1989 breakthrough that bacterial extracellular vesicles contain genetic information, and the recent ISAPP definition on postbiotics, current research suggests bacterial extracellular vesicles derived from probiotic bacteria may be the postbiotics of the future with potential health benefits.

Can probiotics have anti-inflammatory effects worth considering in chronic intestinal diseases?

28 Sep 2022

by Andreu Prados

Inflammation has been involved in the onset of chronic diseases. Probiotics emerge as a potential dietary tool for managing those conditions, partly through their role in immune system modulation and the anti-inflammatory response. Find out what is known about the anti-inflammatory effects of probiotics and their potential applications at the bedside.

Yeast probiotics for the management of gastrointestinal symptoms of IBS

27 Sep 2022

by Andreu Prados

Bacteria and fungi in the human gut microbiota may contribute to the underlying mechanisms of IBS, which means the latter can be explored as a potential target for IBS. This article explores what is known about the role of the gut microbiome and yeast probiotics in irritable bowel syndrome.

Fecal transplants and defined commensal consortia: the pros and cons of restoring the gut microbiome in recurrent Clostridioides difficile infection

19 Sep 2022

by Andreu Prados

Correcting the altered gut microbiome is an important goal in Clostridioides difficile management, but the matter is not addressed by mainstream treatments with antibiotics. This article focuses on where fecal microbiota transplantation and investigational microbiota-based therapeutics stand for C. difficile infection (Part 3)

Small Intestinal Microbiome: An understudied ecosystem in celiac disease

8 Aug 2022

by Heather Galipeau

While celiac disease affects predominantly the small intestine, the contribution of the small intestinal microbiota has been largely understudied. New findings characterize the duodenal microbiota in patients with active celiac disease and explores its functional relevance.

Where do we stand in the management of IBS? Highlights from “IBS days 2022” in Bologna

18 Jul 2022

by Giada De Palma

The third edition of IBS DAYS 2022 provided current advances and a look to future therapeutic approaches on the rapidly advancing field of irritable bowel syndrome. This article summarizes major highlights on diet and gut microbiome interactions of relevance for IBS.

Why microbiome tests are currently of limited value for your clinical practice

4 Jul 2022

by Andreu Prados

Patients usually ask for microbiome tests to manage gut-related issues, to find out what type of diet or food supplement fits best and to get information about the risk of developing chronic diseases. But what kind of information do microbiome tests provide and how reliable are their results for clinical practice?

How can you accurately diagnose and manage Clostridioides difficile infection?

10 Jun 2022

by Andreu Prados

Clostridioides difficile infection is a common cause of diarrhea, not only in hospitals but also in outpatient settings. This article focuses on the diagnosis and treatment of C. difficile infection and includes an updated summary of literature on the latest guidelines (Part 2).

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