Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.
by Mary Ellen Sanders, Patrice D. Cani
Postbiotics and next-generation probiotics are emerging strategies to promote health and manage disease through targeting the human microbiome in a specific way. This article updates what is known in the field and how next-generation probiotics and postbiotics might impact on clinical practice in the foreseeable future.
by Konstantina Zafeiropoulou
Fermented foods, such as yogurt, kefir, kimchi and kombucha, have gained increasing popularity on the market shelves and consumers’ basket. Scientists at Stanford University elucidate how fermented foods may alter gut microbiota profile and reduce inflammatory markers.
by GMFH Editing Team
Ulcerative colitis is a chronic debilitating inflammatory bowel disease with no curative treatment currently available. INRAE scientists have developed a novel predictive model of disease progression in pediatric patients that integrates both gut microbiota and host inflammation data.
by GMFH Editing Team
Fecal microbiota transplantation is being studied in the context of metabolic health, beyond its use for recurrent Clostridioides difficile infection. A new proof-of-principle study reveals that supplementing low-fermentable fiber following fecal microbiota transplantation may improve insulin sensitivity in individuals with severe obesity.
by Rene van den Wijngaard
Long-term treatment of functional dyspepsia with proton-pump inhibitors can alter the gut microbiome. A new pilot randomized, double-blind, placebo-controlled trial suggests the potential of spore-forming probiotics in patients with functional dyspepsia.
by Andreu Prados
Our diet has a huge influence not only on gut microbiota composition but also on its functions. New findings show a fiber-enriched Mediterranean-like diet is well tolerated and influences microbial metabolism in just two weeks, despite no major changes in the core microbiota composition.
by Andreu Prados
Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.
by GMFH Editing Team
Restoring maternal microbes immediately after birth, in a practice dubbed ‘vaginal seeding’, has been suggested as a means of improving microbiome development in cesarean-born neonates. Two new studies come to contradictory findings, however, highlighting the need for more clinical trials before the practice is generalized.
by Andreu Prados
While we have known for a while that a diet consisting of fiber-rich foods reduces the risk of developing chronic diseases and lowers people’s mortality rate, scientists have only recently started elucidating why fiber is beneficial for human health. This article clarifies the definition and health implications of the closely related terms fiber, MACs and prebiotics.
by Patrice D. Cani
The gut microbiome is a potential target of interest for scientists in managing obesity and related metabolic diseases. Scientists have isolated a new-bacterium highly prevalent in the human gut and showing benefits for host metabolism.
