Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.

Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.

The role of gut microbiota in shaping immune responses has led scientists to explore the modulation of the immune system as a mechanism underlying the health benefits of probiotics. A new systematic review and meta-analysis of 9 randomized clinical trials suggest probiotics may reduce the incidence of respiratory and gastrointestinal tract infections in generally healthy children and adults.

Beyond antibiotics, a wide range of commonly used non-antibiotic drugs can affect the gut microbiome. In addition, the gut microbiome can also influence an individual’s response to drugs by affecting their efficacy and safety. What are the implications of the bidirectional interaction between non-antibiotic drugs and the gut microbiome in the clinical setting?

Although the COVID-19 pandemic has shifted the focus of research for scientists worldwide, major breakthroughs in gut microbiome science have been made in 2020. In this last post of the year, we bring you articles from our blog that cover the major advances in the gut microbiome in 2020, from bench to bedside.

The metabolic activity of immune cells is enhanced after a viral infection, such as the one driven by COVID-19. Dietary approaches that support a healthy gut microbiome can benefit the immune system and ensure a good nutritional status that would help the host deal with pathogens.

Many studies have reported changes in gut microbiome composition in patients with inflammatory bowel disease, including ulcerative colitis, when compared with healthy individuals. While that clearly raises the question about the key role played by gut microbes in IBD pathogenesis, we have yet to pinpoint the causative microbes and their mechanisms.