Category : Immune Health

Observational studies in humans have shown that early life exposure to microbes in a variety of situations is associated with a decreased risk of asthma. These include: - Exposure of a pregnant mother to microbes in order to protect her baby - Exposure of children to livestock or dogs - Growing up with numerous siblings Meanwhile, disruption of normal colonization…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Observational studies in humans have shown that early life exposure to microbes in a variety of situations is associated with a decreased risk of asthma. These include: - Exposure of a pregnant mother to microbes in order to protect her baby - Exposure of children to livestock or dogs - Growing up with numerous siblings Meanwhile, disruption of normal colonization…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Dr. Jonathan Braun (MD, PhD) is a physician and researcher interested in how the immune system affects susceptibility to inflammatory bowel disease and cancer. He studies, among other things, microbial-immune commensalism in the intestine, and new strategies in functional immune assessment. He is a professor at UCLA's David Geffen School of Medicine. At the 2014 Harvard Probiotics Symposium, GMFH interviewed…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Jonathan Braun (MD, PhD) is a physician and researcher interested in how the immune system affects susceptibility to inflammatory bowel disease and cancer. He studies, among other things, microbial-immune commensalism in the intestine, and new strategies in functional immune assessment. He is a professor at UCLA's David Geffen School of Medicine. At the 2014 Harvard Probiotics Symposium, GMFH interviewed…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

TH17 (T helper 17) has emerged as a novel potential therapeutic agent for the control of intestinal inflammatory conditions. These cells are most abundant in the small intestinal lamina propris. IL-17 (Interleukin 17A) expressing CD4+T lymphocytes (Th17) cells naturally reside in the intestine's lamina propria where specific cytokines and microbiota, such as segmented filamentous bacteria (SFB), promote the differentiation. To…

Laure Bindels
Satheesh Natarajan, Ph.D., is a postdoctoral research fellow at the Laboratory of Biomedicine and Molecular Immunology, University of Veterinary Medicine and Pharmacy, in Kosice, Slovakia. His work is in immunology and molecular biology.

TH17 (T helper 17) has emerged as a novel potential therapeutic agent for the control of intestinal inflammatory conditions. These cells are most abundant in the small intestinal lamina propris. IL-17 (Interleukin 17A) expressing CD4+T lymphocytes (Th17) cells naturally reside in the intestine's lamina propria where specific cytokines and microbiota, such as segmented filamentous bacteria (SFB), promote the differentiation. To…

Laure Bindels
Satheesh Natarajan, Ph.D., is a postdoctoral research fellow at the Laboratory of Biomedicine and Molecular Immunology, University of Veterinary Medicine and Pharmacy, in Kosice, Slovakia. His work is in immunology and molecular biology.

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

The 2nd congress on targeting microbiota was held at Institut Pasteur in Paris on October 16-17, 2014. Professor Marvin Edeas, chairman of the scientific committee, warned the attendees about avoiding speculation where the challenge might be prevention instead of finding treatment. This should constitute a step "towards clinical revolution". To introduce this state of the art session, Pierre-Henri Gouyon, French National…

GMFH Editing Team
GMFH Editing Team

The 2nd congress on targeting microbiota was held at Institut Pasteur in Paris on October 16-17, 2014. Professor Marvin Edeas, chairman of the scientific committee, warned the attendees about avoiding speculation where the challenge might be prevention instead of finding treatment. This should constitute a step "towards clinical revolution". To introduce this state of the art session, Pierre-Henri Gouyon, French National…

GMFH Editing Team
GMFH Editing Team

In a previous GMFH article, ‘PROBIOTICS’ PART I: A BRANCHING DEFINITION, we covered recent updates to the definition of probiotics as discussed at the October 2013 meeting organized by The International Scientific Association for Probiotics and Prebiotics (ISAPP). Three of the scientific experts on the ISAPP panel – Dr. Francisco Guarner (University Hospital Vall d’Hebron, Barcelona, Spain), Dr. Mary Ellen…

GMFH Editing Team
GMFH Editing Team

In a previous GMFH article, ‘PROBIOTICS’ PART I: A BRANCHING DEFINITION, we covered recent updates to the definition of probiotics as discussed at the October 2013 meeting organized by The International Scientific Association for Probiotics and Prebiotics (ISAPP). Three of the scientific experts on the ISAPP panel – Dr. Francisco Guarner (University Hospital Vall d’Hebron, Barcelona, Spain), Dr. Mary Ellen…

GMFH Editing Team
GMFH Editing Team

Dr. James Versalovic, M.D., Ph.D, is the director of the Texas Children's Hospital Microbiome Center and head of the Pediatric Infectious Diseases Section. He is also a professor at Baylor College of Medicine. As the Gut Microbiota for Health expert on research tools, Dr. Versalovic spoke with us about his pathology and immunology research related to the gut microbiome. How did you become interested in studying the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. James Versalovic, M.D., Ph.D, is the director of the Texas Children's Hospital Microbiome Center and head of the Pediatric Infectious Diseases Section. He is also a professor at Baylor College of Medicine. As the Gut Microbiota for Health expert on research tools, Dr. Versalovic spoke with us about his pathology and immunology research related to the gut microbiome. How did you become interested in studying the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Alexander Khoruts, MD, is a gastroenterologist and Associate Professor of Medicine at University of Minnesota. Since he carried out his first fecal microbiota transplantation (FMT) in 2008, he has conducted research on the procedure and developed protocols for wider clinical use. Dr. Khoruts has spoken about FMT to many audiences and is one of the leading clinical experts on the procedure.…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Alexander Khoruts, MD, is a gastroenterologist and Associate Professor of Medicine at University of Minnesota. Since he carried out his first fecal microbiota transplantation (FMT) in 2008, he has conducted research on the procedure and developed protocols for wider clinical use. Dr. Khoruts has spoken about FMT to many audiences and is one of the leading clinical experts on the procedure.…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Stefka and colleagues studied whether food allergy could be affected by gut microbiota. Germ-free, antibiotic treated and conventional mice have been exposed to a peanut allergen. They found that sensitization to the allergen increased in germ free and antibiotic treated mice. Using a a mix of Clostridia strains, they reversed the sensitization process and demonstrate that this mix could minimize…

GMFH Editing Team
GMFH Editing Team

Stefka and colleagues studied whether food allergy could be affected by gut microbiota. Germ-free, antibiotic treated and conventional mice have been exposed to a peanut allergen. They found that sensitization to the allergen increased in germ free and antibiotic treated mice. Using a a mix of Clostridia strains, they reversed the sensitization process and demonstrate that this mix could minimize…

GMFH Editing Team
GMFH Editing Team

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team