The last 9th Gut Microbiota for Health World Summit hold in Madrid on March updated the science behind diet, the balance between gut microbiota and the immune system, mental health, food intolerances and functional gut disorders, among others. Check out here the Summit’s official report.
Is gut microbiome-lung crosstalk worth considering during the current COVID-19 pandemic?
11 May 2020by Andreu Prados
While patients infected with SARS-CoV-2 typically present with a respiratory illness, certain patients also report gastrointestinal symptoms. The presence of virus receptors in gastrointestinal epithelial cells and an altered gut microbiota composition in some patients might have implications for managing COVID-19.
Analysis of the fetal intestine suggests limited bacterial colonization with potential immunological functions
27 Apr 2020by Andreu Prados
Whether bacterial colonization starts in utero is still a matter for scientific debate. The study of the fetal intestinal content collected from terminated pregnancies reveals some evidence for early bacterial colonization linked to distinct immune imprinting.
Will gut microbiota provide the solution to all of our health problems?
23 Apr 2020by Patrice D. Cani
Gut microbiota, with its close links to metabolism and the immune system, could potentially be a factor that lies at the core of good health. This means it can be positioned at the heart of the processes that influence the risk of contracting different diseases.
Baseline gut microbiota leads to personalized responses to a 7-day amoxicillin-clavulanate challenge in mice
30 Jan 2020by GMFH Editing Team
Gut microbiome responses to antibiotics and their long-lasting effects on the host remain poorly characterized. A new mice study shows that amoxicillin-clavulanate for 7 days leads to personalized changes in gut microbiota composition and colonic transcriptome.
Circadian rhythms are also apparent within our gastrointestinal tract. Two new mice studies show that circadian rhythm and clock genes may also affect intestinal immune cells by boosting the secretion of cytokines that help maintain proper balance of the intestinal barrier.
Findings in mice show alcoholic hepatitis has a microbial component and could be tackled by specific phages
30 Dec 2019by GMFH Editing Team
Imbalances in the gut microbiota composition have been described as a hallmark of certain liver diseases. Yi Duan from the University of California San Diego and colleagues have found in mice that specific phages targeting the gut-dwelling bacterium E. faecalis might be used to treat patients with alcoholic hepatitis.
New findings in healthy adults unravel connections between gut microbiome, metabolome and response to influenza vaccination
17 Oct 2019by GMFH Editing Team
The causal contribution of commensal gut microorganisms in human immune responses is limited. A new study has found that disruptions in the gut microbiome secondary to antibiotics may adversely affect immunity to influenza vaccination in healthy adults.
The availability of glucose and fiber in diet shapes gut microbiome susceptibility to antibiotics in mice
30 Sep 2019by GMFH Editing Team
Scientists struggle to understand why some gut bacteria are sensitive to antibiotics while a fraction of them survive treatment. New research in mice reveals that gut microbial metabolism alongside diet play a key role in modifying the extent of gut microbiome disruption in response to antibiotics.
Scientists have disentangled the role of subsets of immune cells in mediating the development of food allergies through gut microbiota in mice
1 Aug 2019by Andreu Prados
The gut microbiota is a promising target to suppress food allergies through acting via regulatory T cells. New research in mice shed light on mechanisms by which early-life gut microbiota exerts a protective effect against IgE-mediated food allergies.