The role of diet and the gut microbiome in inflammatory bowel disease (IBD) continues to evolve, from shaping disease risk to supporting treatment strategies. In this interview with Richard Hansen and Chen Sarbagili, we discuss key misconceptions, emerging evidence, and what the future may hold for microbiome-based approaches in IBD.

While “gut health” is becoming a popular term, mainly in media and marketing claims but also in the clinical context, researchers have not yet nailed down a definition. Now, a global group of 13 scientists and clinicians updates a consensus definition of gut health and implications from bench to bedside.

The management of disorders of gut-brain interaction based on their causes was a central topic addressed at NeuroGASTRO 2025. In this video interview, Dr. Javier Santos delves into the role of mast cells in postprandial symptoms and the present and future of microbiome-based interventions for bowel disorders.

Key advances in gut microbiome research during 2025

12 Jan 2026

by GMFH Editing Team

2025 has been a productive year in gut microbiome research, spanning metabolic health, neurogastroenterology, immune modulation, and precision nutrition. In this ‘Year in Review’ article, the GMFH editing team describes their pick of the top GMFH-covered advances in 2025, outlining their impact in the clinical setting and implications for current and future research.

Prebiotics have been widely researched in the context of gastrointestinal conditions and might hold potential to influence cognition outcomes by modulating the microbiota-gut-brain axis. A new randomised controlled trial in individuals aged over 60s showed that a prebiotic blend (inulin and fructo-oligosaccharides) is well tolerated and may improve cognition compared with a placebo.

The 13th Gut Microbiota for Health World Summit took place 15-16 March 2025 in Washington, D.C., and it focused on advances in microbiome research to diagnose, prevent, and manage gastrointestinal and extra-intestinal conditions. Find out more about the most valuable takeaways from the event.

Microorganisms in the gut emerge as a potential determining factor for understanding the links between stress response and brain function. New findings highlight the role of gut microbiota as a central regulator of the stress-circadian axis.

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