Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.
It still too early to use probiotics, prebiotics and fermented foods for cognitive performance, concludes a new meta-analysis of randomized controlled trials
23 Nov 2020by GMFH Editing Team
Gut microbiome-targeted interventions are being explored as means of improving cognitive performance. A new meta-analysis of 22 randomized controlled studies has found no significant effect on improving cognition for probiotics, prebiotics and fermented foods, whether alone or used in combination.
Meal ingestion usually induces a wealth of sensations before, during and afterwards. A new brain imaging study reveals sex-specific differences in subjective responses to a palatable meal at thalamic and insular connectivity level in healthy individuals.
Beyond digestive function: meal characteristics and individual responsiveness are major triggers of sensations related to food ingestion
25 May 2020by GMFH Editing Team
Foods are processed in the upper digestive tract and pass into the colon when entering the digestive system. A new paper outlines the impact of food consumption in shaping bidirectional communication between digestive responses and the digestive sensations occurring before, during and after a meal.
The last 9th Gut Microbiota for Health World Summit hold in Madrid on March updated the science behind diet, the balance between gut microbiota and the immune system, mental health, food intolerances and functional gut disorders, among others. Check out here the Summit’s official report.
A new mechanism identifies a gut-brain axis in cerebral cavernous malformation
9 Jan 2020by Manon Oliero
A new publication from Alan T. Tang of the University of Pennsylvania focuses on explaining the relationship between gut microbiota and cerebral cavernous malformation (CCM), which is a neurological disease that leads to hemorrhagic stroke and seizure.
While initial studies focused on characterizing the gut microbiome, there has been a shift in the field towards mechanistic research focusing on microbiome influence on host phenotype. Here, science and medical writer Andreu Prados updates major breakthroughs in the field in 2019.
Gut microbiome diversity associates with sleep quality in healthy adults
18 Nov 2019by Allison Clark
Alterations of the gut microbiota have previously been observed due to sleep deprivation. A novel study shows the close crosstalk between sleep quality and gut microbiome diversity, which is mediated by the pro-inflammatory cytokine IL-6.
A new mice study finds gut microbes affect neurons involved in overcoming fear responses
14 Nov 2019by GMFH Editing Team
How the gut microbial communities affect brain function and behavior remains to be seen. A new mechanistic study in Nature unravels mechanisms by which gut microbiota affects mice adaptation to fear conditioning.
New findings in mice suggest autoimmune mechanisms that originate in the gut are silent drivers of Parkinson’s disease
12 Aug 2019by GMFH Editing Team
Recent studies have widened the immune system and the gut microbiota’s role to the pathophysiology of Parkinson’s disease. Scientists suggest that intestinal infections could act as a trigger in Parkinson’s disease, through affecting mitochondrial antigen presentation and cytotoxic T cells establishment in mice.
