by Megan Mouw
A new study sheds some light on the function of bacterially-produced tryptamine in the gut by showing that it increases colonic fluid secretion in mice through activation of serotonin receptor-4, thus accelerating gastrointestinal transit.
by GMFH Editing Team
A new review clarifies how the gut microbiota regulates Trp metabolism and identifies the underlying molecular mechanisms of these interactions, based on the pathogenesis of human diseases and potential new treatments.
by Kristina Campbell
A new study confirms that help provided by commensal intestinal bacteria present in the GALT (gut-associated lymphoid tissue) means harmless substances from the outside environment can be tolerated.
by Heather Galipeau
In a recently published paper in Nature Medicine, a group led by Harry Sokol at INRA studied how host genes affect the composition and function of the gut microbiota, and in turn, the production of metabolites and intestinal inflammation.