Authors of this paper attempted a meta-analysis of 56 studies on single-strain and multi-strain probiotics for the treatment of IBS, but trials were so heterogeneous when it came to probiotic concentration, duration of treatment, and methodology, that the meta-analysis was abandoned.
Authors of a new Cell paper gave groups of germ-free mice fecal microbiota samples from six healthy adults representing five different habitual diets: American (both a standard diet and a 'primal' diet), Bangladeshi, Malawian, and Amerindian.
In new understandings of IBS, diet and probiotics emerging as promising treatments
2 Oct 2015by Kristina Campbell
When talking about irritable bowel syndrome [IBS], Dr. Eamonn Quigley eschews the term 'functional disorder'. For Quigley, a gastroenterologist and researcher at Houston Methodist Hospital (USA), it's only a matter of time before the disordered physiology of IBS becomes clear.
Previous research has shown that adults with irritable bowel syndrome (IBS) who adopt a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet show an improvement in symptoms within 2 days. Would the low FODMAP diet have the same effect in childhood IBS? Does the gut microbiota predict the success of the diet in children who respond to this dietary intervention?
Dysbiosis -- an abnormal gut microbiota -- is associated with several diseases, including irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
The relationship between symptoms, microbiota, and diet in Irritable Bowel Syndrome
16 May 2015by Paul Enck
Patients with irritable bowel syndrome (IBS) are a heterogenous group, and many report symptoms triggered by diet: most commonly wheat/grains, certain vegetables, milk products, fatty foods, spicy foods, coffee, and alcohol.
Recently, an (open-access) article co-authored with colleagues Hans Törnblom & Magnus Simrén appeared in Nature Reviews Gastroenterology and Hepatology - Crosstalk at the mucosal border: importance of the gut microenvironment in IBS.
While a lot of research in gut microbiota is focused on the bacterial community, little research data is available on the microeukaryotic community.
Is Parkinson´s Disease a gastrointestinal disorder, with microbiota contribution?
27 Dec 2014by Paul Enck
The pathomechanism of Parkinson´s disease (PD) is well known but its origin is far from completely understood. The fact that among the prodromal signs of PD are constipation and a number of other (autonomically regulated) symptoms that occur years before
I participated in the "Targeting microbiota" congress at Pasteur Institute because I considered the topics discussed very interesting and relevant to my research. For me microbiome conferences are still a rather foreign territory, but I very much like to talk
