Inflammation has been involved in the onset of chronic diseases. Probiotics emerge as a potential dietary tool for managing those conditions, partly through their role in immune system modulation and the anti-inflammatory response. Find out what is known about the anti-inflammatory effects of probiotics and their potential applications at the bedside.

Bacteria and fungi in the human gut microbiota may contribute to the underlying mechanisms of IBS, which means the latter can be explored as a potential target for IBS. This article explores what is known about the role of the gut microbiome and yeast probiotics in irritable bowel syndrome.

Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.

Little is known about the relationship between diet, the composition and function of the gut microbiota and clinical symptoms of IBS. New findings identify how IBS symptom severity is related to a higher intake of foods with poor nutritional quality and gut microbiome features at both subspecies level and metabolic pathways involved in carbohydrate metabolism.

Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.

Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.