by Rene van den Wijngaard
Long-term treatment of functional dyspepsia with proton-pump inhibitors can alter the gut microbiome. A new pilot randomized, double-blind, placebo-controlled trial suggests the potential of spore-forming probiotics in patients with functional dyspepsia.
by Andreu Prados
Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.
by Joël Doré
Little is known about the relationship between diet, the composition and function of the gut microbiota and clinical symptoms of IBS. New findings identify how IBS symptom severity is related to a higher intake of foods with poor nutritional quality and gut microbiome features at both subspecies level and metabolic pathways involved in carbohydrate metabolism.
by Andreu Prados
The low FODMAP diet has been shown to be effective in managing the symptoms of IBS as second-line dietary advice when healthy eating approaches have failed to reduce symptoms. However, this eliminative diet is not without its challenges, which can be overcome by following the advice found below.
Analysing the molecular and biochemical mechanisms disturbing the complex network of communication is key to our understanding of the pathophysiology of the functional GI disorders. Together with ESNM we have prepared an exciting webinar series under the topic: Microbiota and Gut-Brain Connection: A new Frontier in Neurogastroenterology. This free resource is a great opportunity to hear leading worldwide experts presenting the most recent findings on this topic.
by GMFH Editing Team
Diet is becoming increasingly popular as a means of managing IBS symptoms. A new study in 95 adults with IBS examines diet-gut microbiota associations and concludes that baseline gut microbiota is not a good predictor of clinical response to a low FODMAP diet or probiotic intervention.
by Rene van den Wijngaard
Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.
by GMFH Editing Team
The heterogeneity of cross-sectional IBS studies has limited elucidating the gut ecosystem’s overall involvement in the disease pathogenesis. New longitudinal research that integrates multi-omics, patient and gastrointestinal data reveals previously unidentified targets that accompany changes in IBS activity.
Irritable bowel syndrome is one of the most common disorders diagnosed by gastroenterologists. Peppermint oil, specific probiotics, psyllium supplementation, first-line IBS dietary advice, and a low FODMAP diet can aid in improving IBS symptoms.
Diet is one of the cornerstones for managing IBS. The study of mechanisms of action coupled with symptom-related data are valuable for understanding the role of exclusion diets in patients with IBS.
