Dietary fibers, known to regulate intestinal inflammation and gut barrier functions, have been avoided by patients with inflammatory bowel diseases (IBD) to avoid flare-ups. However, recent findings suggest that if fiber type, patient immunological condition, and the fermentative ability of the gut microbiota are taken into account, they could be beneficial and prevent relapses.
It is largely recognized that a high-salt diet can lead to hypertension. A new randomized controlled trial reports that, particularly in females with untreated hypertension, reducing salt intake to recommended levels is linked to decreased blood pressure, more compliant blood vessels and increased serum levels of short-chain fatty acids.
Could increasing delivery of propionate to the human colon be a potential way of improving glucose homeostasis in overweight or obese individuals?
6 May 2019by Andreu Prados
Colonic propionate has been suggested as a potential target to improve obesity-related metabolic disorders. Based on new research, colonic propionate delivery could be a novel solution to improve metabolism and inflammation in overweight or obese subjects.
Fermentable fibers affect the structure and function of gut microbiota, with potato starch leading to the greatest increase in short-chain fatty acids
4 Mar 2019by Andreu Prados
Resistant starch is a highly fermentable fiber, although it’s considered to be an insoluble fiber. What is more interesting is the fact that the food source of resistant starch matters, as scientists show not all foods that are high in resistant starch drive identical changes in gut microbiota’s functional diversity.
Gut microbiota is the human body's most complex, diverse and numerous ecosystem of all, particularly in the caecum, where the density of microorganisms is the highest.
The most significant achievements in gut microbiome science in 2018
27 Dec 2018by GMFH Editing Team
GMFH continue to cover the important progress made in our knowledge of the gut microbiota's impact on wellbeing and disease.
Regulatory T cells improve gut barrier integrity through preserving colonic short-chain fatty acid levels in cirrhotic mice
13 Dec 2018by Oriol Juanola & Rubén Francés
Mice without the capacity to produce mature B and T lymphocytes showed an increased gut permeability.
Omega-3 polyunsaturated fatty acids may lead to a reversible increase in some gut bacteria in healthy adults
29 Nov 2018by Stéphane Schneider
The researchers analyzed the effects of oral high-dose omega-3 PUFA on the fecal microbiota of 22 healthy middle-aged volunteers.
Exposure to viral and bacterial infections early in life, especially in the setting of certain genetic predispositions, may increase an individual’s risk for developing food sensitivities.
Human-origin probiotic-cocktail inhibits the growth of uropathogenic bacteria and increases production of SCFAs
8 Oct 2018by Megan Mouw
Researchers have developed a new probiotic-cocktail of infant-gut origin that modulates the gut microbiota of mice (in-vivo) and human feces (ex-vivo) by increasing native production of SCFAs.
