A recent review by Dr. Stacey Lockyer from the British Nutrition Foundation in London (United Kingdom) and Dr. Anne Nugent from the University College Dublin in Dublin (Ireland) summarises reported health effects of RS and explores the potential mechanisms of action that underpin them.

In a recent paper by Perry et al., researchers describe an investigation into the putative mechanisms by which gut microbiota alterations may lead to obesity, insulin resistance, and metabolic syndrome. Authors describe increased production of acetate by altered gut microbiota in rats. They link this to activation of the parasympathetic nervous system, increased glucose-stimulated insulin secretion, higher ghrelin secretion, hyperphagia, and obesity. Thus, they point to increased acetate production as a driver of metabolic syndrome.

A recent review article, led by Dr Rajiv R. Ratan from the Brain and Mind Research Institute (BMRI) in New York, explores the provocative idea a high-fibre diet can prevent neurodegeneration in the brain by increasing butyrate in the colon.

As MyNewGut, a research initiative involving thirty organizations from fifteen countries, continued to carry out its research program on prebiotic fibres and the gut microbiota, project participants held a workshop before the International Dietary Fibre Conference 2015 in Paris.