Emerging studies support the relationship between the human gut microbiome and organ function outside the gut. Find out more about the knowns and unknowns on how the gut communicates with other parts of the body, involving the gut, the brain, the lungs, the skin, and even the heart, and why it matters to your health.

The fundamental role of gut bacteria in overall health has been recognized for years. Imbalances in its composition have been linked to autoimmune, gastrointestinal, and metabolic diseases, and now also to cardiovascular conditions. Increasingly, scientists are studying the gut-heart axis and suggest that the gut microbiota could become a new therapeutic target for preventing and treating heart diseases.

We continue our series on the gut axis, this time focusing on the gut-skin connection. You might have noticed it yourself—how a heavy, sugary meal can lead to breakouts the next day, or how certain food allergies can trigger rashes. This is the gut-skin axis at work, demonstrating an association between the health of our gut and the condition of our skin, and vice versa.

The gut, its microbiota, and the liver communicate through complex interactions. This communication, known as the gut-liver axis, plays a crucial role in maintaining liver health and preventing disease. We will explore the role of gut microbiota in the gut-liver axis and delve into the emerging microbiota-based therapies that hold promise for liver diseases.

Scientists are starting to elucidate the roots of gastrointestinal symptoms that appear after a meal in people with irritable bowel syndrome. Current research highlights the immune drivers of gut pain, which could offer clues on how to treat IBS.

Two hospitals in Barcelona, the Clínic and Bellvitge, have launched Spain's first Fecal Microbiota Bank. Their goal is to obtain donations of stool from healthy individuals to perform microbiota transplants on patients suffering from potentially fatal infections of bacteria known as C. difficile infections. We step into the fecal microbiota transfer units of both hospitals to learn how they operate and meet some of the donors.

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