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Could targeting the gut help treat type 2 diabetes? Intestinal bioactive compounds offer clues for developing new antidiabetics

22 Oct 2020

by Patrice D. Cani

Enteric neurons have recently emerged as a new target in the management of type 2 diabetes. The findings in mice and humans identify new intestinal bioactive compounds released after prebiotic administration, with potential for improving glucose metabolism.

Exercise and metabolism: what role does the gut microbiome play?

29 Apr 2020

by Allison Clark

Increasing evidence suggests that imbalanced gut microbiota may play a role in insulin resistance in Type 2 Diabetes patients and exercise has shown to have positive effects on the gut microbiome and metabolism.

Microbial signatures identified in the liver, adipose tissue and blood of people with obesity and diabetes

23 Mar 2020

by Patrice D. Cani

Individuals with obesity and type 2 diabetes have shown an altered gut microbiome composition. A new study has discovered tissue bacterial signatures linked to type 2 diabetes.

Gut microbiota composition tied to type 2 diabetes remission following bariatric surgery in obese diabetic women

9 Mar 2020

by Andreu Prados

Our gut microbiota profile may help us understand the contribution of bariatric surgery to weight loss. New findings reveal gut microbiota composition before Roux-en-Y gastric bypass is associated with type 2 diabetes remission in obese diabetic women.

Scientists identify gut microbiome taxonomic and functional profiles that uniquely characterize obesity and type 2 diabetes

7 Nov 2019

by GMFH Editing Team

Ruling out the specific contribution of obesity and type 2 diabetes in gut microbiome variation is a challenge. Louise Thingholm and colleagues have found that while obesity is linked to gut microbiome variation, gut microbiome associations with type 2 diabetes are modest.

A high fiber diet may promote specific short-chain fatty acid producers to achieve better metabolic control in type 2 diabetes

26 Mar 2018

by Andreu Prados

A new randomized clinical trial has found that promotion of a select group of gut bacteria by a diet high in diverse fibers may lead to better blood glucose and lipid control and greater weight loss in people with T2DM.

Gut microbiota may help predict which patients with type 2 diabetes will respond to the anti-diabetic drug Acarbose

15 Jan 2018

by Andreu Prados

A new multicentre, randomised controlled clinical trial, led by Prof. Weiqing Wang from the Shanghai National Research Centre for Endocrine and Metabolic Diseases at the Shanghai Jiaotong University School of Medicine in Shanghai (China), has found that gut microbiota may help predict which patients with T2D respond to treatment with Acarbose.

GMFH to take part in the 21st International Congress of Nutrition (ICN)

18 Sep 2017

by GMFH Editing Team

Gut Microbiota for Health is pleased to announce its participation at the 21st International Congress of Nutrition (ICN). 

New insights on how altered gut microbiota mediates some of metformin’s therapeutic effects

24 Jul 2017

by Andreu Prados

A new randomized, placebo-controlled, double-blind study has found both clinical and mechanistic evidence that metformin’s improved blood glucose control is achieved through modulation of the gut microbiota.

Can gut bacteria be used for early diagnosis of type 2 diabetes?

6 Apr 2016

by Andreu Prados

The prevalence of type 2 diabetes (T2D) is increasingly rapidly around the globe and has challenged researchers to investigate the underlying pathophysiological mechanisms.

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