Gut microbiota and weight management

26 May 2025

by Amandine Everard, Andreu Prados

Microbes living in your digestive tract may help you achieve or maintain a healthy body weight by influencing your food intake behaviors. This article delves into what scientists know and do not know about gut microbiota and obesity and provides science-backed tools for leveraging the microbes in your gut to achieve a healthier body weight.

Fecal microbiota transplantation is being studied in the context of metabolic health, beyond its use for recurrent Clostridioides difficile infection. A new proof-of-principle study reveals that supplementing low-fermentable fiber following fecal microbiota transplantation may improve insulin sensitivity in individuals with severe obesity.

We have known for a while that obesity has a microbial component. Now, a team of scientists led by Patrice D. Cani reports a novel bacterium isolated from the human gut that counteracts diet-induced obesity, inflammation and glucose dysregulation in mice.

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