Gut microbiota alterations in obesity remain the subject of debate. Writing in Nature, Vieira-Silva and colleagues found that the undesirable Bacteroides 2 enterotype was more frequent in people with a higher body mass index, but not if they were taking statins.

Gut microbiota, with its close links to metabolism and the immune system, could potentially be a factor that lies at the core of good health. This means it can be positioned at the heart of the processes that influence the risk of contracting different diseases.

Large inter-individual variability exists regarding how our gut microbiota responds to dietary intervention. New findings in mice and people with obesity show that ‘responders’ to inulin may be identifiable from their gut microbiota before they receive the intervention.

Could our gut microbiota mediate the impact of bariatric surgery on severe obesity? A new cross-sectional study has found that interactions between the gut microbiota and bile acids metabolism may partially mediate the success of bariatric surgery in the medium term.