by Hervé Blottière
New findings reveal the gut microbiome evolves gradually from healthy people, across those with genetic risk of Parkinson’s disease to patients who are symptomatic.
by Giovana Martucelli
Blastocystis has long been viewed mainly as a marker of parasitic infection. Emerging research reviewed here suggests that its presence is not necessarily linked to disease, but may instead reflect greater microbial diversity and metabolic health in certain contexts.
by Andreu Prados
While diet is a major determinant of the human gut microbiome, little is known about diet-microbiome associations at species-level resolution. New findings from the Human Phenotype Project found species-level, food-specific associations validated at population scale that might guide personalized nutrition.
by Nathalie Rolhion, Harry Sokol
Antibiotic treatments can profoundly disrupt gut microbiome structure and function. This article reviews new findings showing how Saccharomyces boulardii CNCM I-745 helps preserve microbial activity and metabolic resilience during antibiotic stress, with insights from advanced in vitro models and immune assays.
by Mónica Quinzo
The definition of a prebiotic has evolved from a focus on colonic fiber to a complex ecological strategy. This article traces the concept's 30-year journey, highlighting the shift from non-digestible carbohydrates to the latest expert recommendations.
by GMFH Editing Team
Microbiome tests are becoming popular among the lay public and health professionals to diagnose and manage microbiome-related conditions. A new consensus involving scientists in basic and translational science updates the ins and outs of microbiome testing in clinical practice.
by Andreu Prados
As antibiotic-resistant infections continue to rise worldwide, phage therapy emerges as a promising alternative to antibiotics to tackle this public health threat.
Writing in Nature Reviews Microbiology, a group of scientists updates the healthy human microbiome concept by combining independent measures of both the host and the microbial community health, and proposes a framework for discovering health and disease-associated microbial signatures in diverse populations.
An altered gut microbiome has been linked to various chronic diseases. New findings in mice reveal that a disrupted paternal gut microbiome impacts pregnancy health and increases the risk of growth issues in their future offspring.
by Andrea Costantino
Chronic abdominal pain, diarrhea, constipation, and bloating are common gastrointestinal symptoms. While a structural or an organic disease can be suspected because of the symptoms and is often easy to be diagnosed by endoscopy or imaging methods, sometimes gastrointestinal symptoms are not related to any alteration that may be seen through diagnostic techniques, and consequently have been classified under the umbrella of “disorders of gut-brain interaction”.
