by Nathalie Rolhion, Harry Sokol
Antibiotic treatments can profoundly disrupt gut microbiome structure and function. This article reviews new findings showing how Saccharomyces boulardii CNCM I-745 helps preserve microbial activity and metabolic resilience during antibiotic stress, with insights from advanced in vitro models and immune assays.
by Mónica Quinzo
The definition of a prebiotic has evolved from a focus on colonic fiber to a complex ecological strategy. This article traces the concept's 30-year journey, highlighting the shift from non-digestible carbohydrates to the latest expert recommendations.
by GMFH Editing Team
Microbiome tests are becoming popular among the lay public and health professionals to diagnose and manage microbiome-related conditions. A new consensus involving scientists in basic and translational science updates the ins and outs of microbiome testing in clinical practice.
by Andreu Prados
As antibiotic-resistant infections continue to rise worldwide, phage therapy emerges as a promising alternative to antibiotics to tackle this public health threat.
Writing in Nature Reviews Microbiology, a group of scientists updates the healthy human microbiome concept by combining independent measures of both the host and the microbial community health, and proposes a framework for discovering health and disease-associated microbial signatures in diverse populations.
An altered gut microbiome has been linked to various chronic diseases. New findings in mice reveal that a disrupted paternal gut microbiome impacts pregnancy health and increases the risk of growth issues in their future offspring.
by Andrea Costantino
Chronic abdominal pain, diarrhea, constipation, and bloating are common gastrointestinal symptoms. While a structural or an organic disease can be suspected because of the symptoms and is often easy to be diagnosed by endoscopy or imaging methods, sometimes gastrointestinal symptoms are not related to any alteration that may be seen through diagnostic techniques, and consequently have been classified under the umbrella of “disorders of gut-brain interaction”.
by Andreu Prados, Joël Doré
The 11th Gut Microbiota for Health World Summit focused on emerging gut microbiome-targeted treatments in digestive, immune and cardiometabolic health. This post highlights the major take-aways from the conference and explores how they might impact clinical practice in the foreseeable future.
by Heather Galipeau
While celiac disease affects predominantly the small intestine, the contribution of the small intestinal microbiota has been largely understudied. New findings characterize the duodenal microbiota in patients with active celiac disease and explores its functional relevance.
by Andreu Prados
Patients usually ask for microbiome tests to manage gut-related issues, to find out what type of diet or food supplement fits best and to get information about the risk of developing chronic diseases. But what kind of information do microbiome tests provide and how reliable are their results for clinical practice?
