Category : C-Diff

This post is a shortened version of the original article published in Science Trends on July 11, 2018. If – for whatever reason – a single toxic bacterial species – Clostridium difficile (C-diff) – has taken over your entire gut ecosystem, has banished many of the commensal gut bacteria needed for a healthy life, and does not respond any longer…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

This post is a shortened version of the original article published in Science Trends on July 11, 2018. If – for whatever reason – a single toxic bacterial species – Clostridium difficile (C-diff) – has taken over your entire gut ecosystem, has banished many of the commensal gut bacteria needed for a healthy life, and does not respond any longer…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The administration of broad-spectrum antibiotics is an important risk factor for Clostridium difficile infection (CDI) in the Western world. Recent research has suggested that probiotics may help reduce the incidence of C. difficile-associated diarrhea (CDAD) among children and adults in both hospital and outpatient settings. A new systematic review and meta-analysis, led by Dr. Bradley Johnston from Dealhousie University (Canada),…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The administration of broad-spectrum antibiotics is an important risk factor for Clostridium difficile infection (CDI) in the Western world. Recent research has suggested that probiotics may help reduce the incidence of C. difficile-associated diarrhea (CDAD) among children and adults in both hospital and outpatient settings. A new systematic review and meta-analysis, led by Dr. Bradley Johnston from Dealhousie University (Canada),…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team

In the new Gut Microbiota for Health “Clinical Minute” series, we get a scientific expert’s take on gut-microbiota-related questions of interest to healthcare professionals. TOPIC: Should probiotics be used for prevention of Clostridium difficile infection? Dr. Nicole T. Shen is a first year gastroenterology and hepatology fellow in the Division of Gastroenterology and Hepatology at Weill Department of Medicine, Weill…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

In the new Gut Microbiota for Health “Clinical Minute” series, we get a scientific expert’s take on gut-microbiota-related questions of interest to healthcare professionals. TOPIC: Should probiotics be used for prevention of Clostridium difficile infection? Dr. Nicole T. Shen is a first year gastroenterology and hepatology fellow in the Division of Gastroenterology and Hepatology at Weill Department of Medicine, Weill…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Recently, there has been a huge change in the perception of microbial diseases and a shift in the understanding of how to treat them. It is now recognized that there are few disorders that can be attributed to the presence or absence of a single organism. Rather, the structure of the entire community of microbes constituting the human microbiota often…

Melissa Agnello
Melissa Agnello is a postdoctoral scholar at the University of California, Los Angeles. Her research focuses on the bacteria and other resident microbes that live in the mouth, how they cause diseases such as caries, and how manipulating them can lead to new treatments and/or preventions.

Recently, there has been a huge change in the perception of microbial diseases and a shift in the understanding of how to treat them. It is now recognized that there are few disorders that can be attributed to the presence or absence of a single organism. Rather, the structure of the entire community of microbes constituting the human microbiota often…

Melissa Agnello
Melissa Agnello is a postdoctoral scholar at the University of California, Los Angeles. Her research focuses on the bacteria and other resident microbes that live in the mouth, how they cause diseases such as caries, and how manipulating them can lead to new treatments and/or preventions.

Clostridium difficile infection (CDI) is a common infection in which alterations in gut microbiota play an important role in increased susceptibility. Although current research is assessing several clinical features that may predict CDI treatment response, there is a need for consistent predictors of response and recurrence in patients with a first occurrence of CDI. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Clostridium difficile infection (CDI) is a common infection in which alterations in gut microbiota play an important role in increased susceptibility. Although current research is assessing several clinical features that may predict CDI treatment response, there is a need for consistent predictors of response and recurrence in patients with a first occurrence of CDI. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

In a recent issue of Annals of Internal Medicine, Cammarota et al. showed that the implementation of a fecal microbiota transplantation (FMT) program, available from June 2013 in the A. Gemelli University Hospital, an Italian academic tertiary care centre, led to fewer surgical procedures for severe C. difficile infection (CDI). Between January 2010 and April 2015, 901 patients with CDI…

GMFH Editing Team
GMFH Editing Team

In a recent issue of Annals of Internal Medicine, Cammarota et al. showed that the implementation of a fecal microbiota transplantation (FMT) program, available from June 2013 in the A. Gemelli University Hospital, an Italian academic tertiary care centre, led to fewer surgical procedures for severe C. difficile infection (CDI). Between January 2010 and April 2015, 901 patients with CDI…

GMFH Editing Team
GMFH Editing Team