Archives des C-Diff

Fecal transplants and defined commensal consortia: the pros and cons of restoring the gut microbiome in recurrent Clostridioides difficile infection

19 Sep 2022

by Andreu Prados

Correcting the altered gut microbiome is an important goal in Clostridioides difficile management, but the matter is not addressed by mainstream treatments with antibiotics. This article focuses on where fecal microbiota transplantation and investigational microbiota-based therapeutics stand for C. difficile infection (Part 3)

How can you accurately diagnose and manage Clostridioides difficile infection?

10 Jun 2022

by Andreu Prados

Clostridioides difficile infection is a common cause of diarrhea, not only in hospitals but also in outpatient settings. This article focuses on the diagnosis and treatment of C. difficile infection and includes an updated summary of literature on the latest guidelines (Part 2).

New free Webinar Series 2022 on Clostridioides difficile

21 Mar 2022

by GMFH Editing Team

In a series of 7 webinar this programme will develop a full picture of the C. difficile infection (CDI) reaching from the importance of a healthy gut microbiota, to its detection and testing methods to current and future therapeutic approaches.

Clostridioides difficile infection remains an unfamiliar subject for clinicians

25 Feb 2022

by Andreu Prados

Clostridioides difficile infection is the most frequent cause of antibiotic-associated diarrhea in the hospital setting that has increased in severity. This article looks at the risk factors for developing C. difficile-associated disease, the spectrum of manifestations and the impact of the COVID-19 pandemic on the occurrence of C. difficile infection.

The most significant achievements in gut microbiome science in 2018

27 Dec 2018

by GMFH Editing Team

GMFH continue to cover the important progress made in our knowledge of the gut microbiota's impact on wellbeing and disease.

Fecal microbiota transfer (FMT) – past, present, and (no) future

10 Sep 2018

by Paul Enck

The ultimate goal would be to create an "artificial stool", a consortium of commensal bacteria fermented and harvested in vitro,

A recent Cochrane review shows that probiotics appear to be effective and safe in preventing Clostridium difficile infection

27 Aug 2018

by Paul Enck

A new systematic review and meta-analysis concludes that probiotics are associated with a lower risk of symptomatic C. difficile infection.

A review examines the role of dietary transition metals on host microbiota and risk of disease

12 Jul 2018

by Andreu Prados

A new review focuses on mechanisms leading to increased susceptibility to bacterial infection in the context of interactions between dietary transition metals,

A diet rich in dietary plant polysaccharides suppresses Clostridium difficile infection in mice

10 May 2018

by Andreu Prados

A new study has found that microbiota-accessible carbohydrate-utilizing bacteria and short-chain fatty acids generated during their fermentation prevent C. difficile infection perpetuation in mice.

Gut Microbiota for Health releases the first of two summary documents on gut microbiota and probiotics

29 Jan 2018

by GMFH Editing Team

The scientific knowledge on probiotics is advancing very quickly—stay tuned for the second GMFH "best of probiotics" document.