Crohn’s disease is an inflammatory bowel disease linked to an imbalance in the gut microbiome. Now, researchers at McMaster University have found in mice a way to target and 'turn off' only the bad gut bacteria using specially trained, precision viruses. This breakthrough paves the way for treatments tailored to each patient.
For patients with celiac disease on a gluten-free diet, fiber may work best with the right gut microbes
27 Apr 2026by Heather Galipeau, Mark Wulczynski
A new study reveals that the benefits of dietary fiber in celiac disease depend not only on intake, but also on the presence of specific gut microbes capable of metabolizing it. These findings highlight the need for more personalized dietary strategies beyond the gluten-free diet.
Specific probiotic species and strains could help manage chronic constipation in adults
2 Feb 2026by Andreu Prados
Chronic constipation affects around one in ten adults worldwide. The new British Dietetic Association’s guidelines show that psyllium, certain probiotic strains and magnesium oxide supplements can help to improve constipation.
From colonic food to systems biology: the 30th anniversary of the prebiotic concept
17 Dec 2025by Mónica Quinzo
The definition of a prebiotic has evolved from a focus on colonic fiber to a complex ecological strategy. This article traces the concept's 30-year journey, highlighting the shift from non-digestible carbohydrates to the latest expert recommendations.
Fecal microbiota transplantation unable to induce remission at 8 weeks in adults with Crohn’s disease
17 Nov 2025by Karen Madsen
Previous clinical studies have shown a promising role of fecal microbiota transplantation to induce remission in ulcerative colitis and maintain steroid-induced Crohn’s disease remission. A new double-blind, placebo-controlled trial found fecal microbiota transplantation is not effective at inducing clinical or endoscopic remission in adults with Crohn’s disease.
This Halloween, we’re celebrating some microbes that sound scary but play a vital role in keeping us healthy. Behind their ghostly names lie fascinating stories of cooperation, balance, and invisible teamwork inside our gut.
Patients’ expectations and beliefs in IBS: Why gluten and wheat might not be the culprit
30 Sep 2025by Andreu Prados
Many patients with IBS find that wheat or gluten triggers gastrointestinal symptoms, prompting them to exclude these foods from their diets. A new study highlights how patients’ expectations and beliefs shape symptom modulation and dietary choices in IBS.
Prebiotics have been widely researched in the context of gastrointestinal conditions and might hold potential to influence cognition outcomes by modulating the microbiota-gut-brain axis. A new randomised controlled trial in individuals aged over 60s showed that a prebiotic blend (inulin and fructo-oligosaccharides) is well tolerated and may improve cognition compared with a placebo.
After two decades of scientific exploration, the human microbiome has emerged as a critical determinant of health and disease. Fueled by multi-omics technologies and machine learning, the field has advanced from correlation-based observations to establishing causal relationships. This article presents recent and compelling examples of microbiome-based treatments that are ripe for clinical adoption and discusses challenges and opportunities facing the field based on expert interviews conducted by the GMFH team.
Emerging research suggests a complex interaction between the gut microbiome and endometriosis. Recent studies have begun to explore the impact of dietary interventions on endometriosis.
