Category : Infections

The gut microbiota has wide-ranging effects on host physiology and is an important determinant of health and disease. As we have learned over the past two decades, these effects are not limited to the gastrointestinal tract, but can influence host functions throughout the body.  A great deal of research has focused on understanding the mechanisms by which microbes influence host…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

The gut microbiota has wide-ranging effects on host physiology and is an important determinant of health and disease. As we have learned over the past two decades, these effects are not limited to the gastrointestinal tract, but can influence host functions throughout the body.  A great deal of research has focused on understanding the mechanisms by which microbes influence host…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

The current antibiotic resistance epidemic is reaching levels higher than previously reported. And the roots of this epidemic can be found not only in an increase in outpatient antibiotic use, but also on the high proportions of resistant bacteria transmitted from food-producing animals. The effects of antibiotics on human gut bacterial diversity is of particular relevance during early life. It…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The current antibiotic resistance epidemic is reaching levels higher than previously reported. And the roots of this epidemic can be found not only in an increase in outpatient antibiotic use, but also on the high proportions of resistant bacteria transmitted from food-producing animals. The effects of antibiotics on human gut bacterial diversity is of particular relevance during early life. It…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Other than gut microbiota's well-known functions, which include nutrient metabolism and absorption, xenobiotic and drug metabolism, and immune development, its role in protecting against pathogens has been poorly characterized. Previous research has identified some microbiota-mediated colonization resistance mechanisms, while little is known about whether microbial metabolites may also limit pathogen colonization. A new study, led by Dr. Denise Monack from…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Other than gut microbiota's well-known functions, which include nutrient metabolism and absorption, xenobiotic and drug metabolism, and immune development, its role in protecting against pathogens has been poorly characterized. Previous research has identified some microbiota-mediated colonization resistance mechanisms, while little is known about whether microbial metabolites may also limit pathogen colonization. A new study, led by Dr. Denise Monack from…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

This post is a shortened version of the original article published in Science Trends on July 11, 2018. If – for whatever reason – a single toxic bacterial species – Clostridium difficile (C-diff) – has taken over your entire gut ecosystem, has banished many of the commensal gut bacteria needed for a healthy life, and does not respond any longer…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

This post is a shortened version of the original article published in Science Trends on July 11, 2018. If – for whatever reason – a single toxic bacterial species – Clostridium difficile (C-diff) – has taken over your entire gut ecosystem, has banished many of the commensal gut bacteria needed for a healthy life, and does not respond any longer…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The administration of broad-spectrum antibiotics is an important risk factor for Clostridium difficile infection (CDI) in the Western world. Recent research has suggested that probiotics may help reduce the incidence of C. difficile-associated diarrhea (CDAD) among children and adults in both hospital and outpatient settings. A new systematic review and meta-analysis, led by Dr. Bradley Johnston from Dealhousie University (Canada),…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The administration of broad-spectrum antibiotics is an important risk factor for Clostridium difficile infection (CDI) in the Western world. Recent research has suggested that probiotics may help reduce the incidence of C. difficile-associated diarrhea (CDAD) among children and adults in both hospital and outpatient settings. A new systematic review and meta-analysis, led by Dr. Bradley Johnston from Dealhousie University (Canada),…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

One of the strategies used by vertebrate hosts to defend against bacterial pathogens is that of sequestering transition metals required for intracellular and extracellular pathogen survival. This process is called “nutritional immunity” and, in response, bacteria have evolved strategies to access metals and counteract this host mechanism of defense. A new review, led by Dr. Christopher Lopez and Prof. Eric…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Our gut microbiota may be involved in mediating interactions between the enteric nervous system and central nervous system (CNS) through the gut-brain axis. The impact of commensal gut microbes on CNS functions have been studied mostly in mice. As such, the antibiotic-induced CNS consequences of manipulating humans' gut microbiota are still unknown. A new double-blinded randomized study led by our…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Our gut microbiota may be involved in mediating interactions between the enteric nervous system and central nervous system (CNS) through the gut-brain axis. The impact of commensal gut microbes on CNS functions have been studied mostly in mice. As such, the antibiotic-induced CNS consequences of manipulating humans' gut microbiota are still unknown. A new double-blinded randomized study led by our…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team