by Andreu Prados
Clostridioides difficile infection is the most frequent cause of antibiotic-associated diarrhea in the hospital setting that has increased in severity. This article looks at the risk factors for developing C. difficile-associated disease, the spectrum of manifestations and the impact of the COVID-19 pandemic on the occurrence of C. difficile infection.
by GMFH Editing Team
The mechanisms underlying associations between yogurt consumption and a reduced risk of negative health outcomes have not been widely studied. A cross-sectional study now suggests that maintaining normal gut barrier function is a new mechanism that supports the benefits of consuming yogurt.
by GMFH Editing Team
Gut microbiome responses to antibiotics and their long-lasting effects on the host remain poorly characterized. A new mice study shows that amoxicillin-clavulanate for 7 days leads to personalized changes in gut microbiota composition and colonic transcriptome.
Circadian rhythms are also apparent within our gastrointestinal tract. Two new mice studies show that circadian rhythm and clock genes may also affect intestinal immune cells by boosting the secretion of cytokines that help maintain proper balance of the intestinal barrier.
by GMFH Editing Team
Scientists struggle to understand why some gut bacteria are sensitive to antibiotics while a fraction of them survive treatment. New research in mice reveals that gut microbial metabolism alongside diet play a key role in modifying the extent of gut microbiome disruption in response to antibiotics.
by Andreu Prados
The mechanisms that link changes in gut microbiome composition and an increased risk of cardiovascular disease remain elusive. Changes in the gut microbiome related to aging may mediate arterial dysfunction, coupled with a normalization of inflammation, suggests a new mice study.
by GMFH Editing Team
Contrary to common drugs, probiotics can evolve during treatment within the host. Scientists have tracked the behavior of E. coli Nissle 1917 in the mouse’s gut and shown that unbalanced gut microbiomes and different diets may affect how this bacterium evolves across the gastrointestinal tract.
by GMFH Editing Team
GMFH continue to cover the important progress made in our knowledge of the gut microbiota's impact on wellbeing and disease.
by Andreu Prados
The University of Birmingham and King’s College have developed a new bioinformatics gene function prediction method
by Oriol Juanola & Rubén Francés
Mice without the capacity to produce mature B and T lymphocytes showed an increased gut permeability.
