Category : Immune Health

Our gut microbiota may be involved in mediating interactions between the enteric nervous system and central nervous system (CNS) through the gut-brain axis. The impact of commensal gut microbes on CNS functions have been studied mostly in mice. As such, the antibiotic-induced CNS consequences of manipulating humans' gut microbiota are still unknown. A new double-blinded randomized study led by our…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Our gut microbiota may be involved in mediating interactions between the enteric nervous system and central nervous system (CNS) through the gut-brain axis. The impact of commensal gut microbes on CNS functions have been studied mostly in mice. As such, the antibiotic-induced CNS consequences of manipulating humans' gut microbiota are still unknown. A new double-blinded randomized study led by our…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Clostridium difficile infection (CDI) represents a major healthcare concern that causes diarrhea and usually affects people who have recently been treated with antibiotics or have had an extended stay in a healthcare setting. It can also spread easily to others. Although previous experimental research has shown that a fiber-deprived diet leads to a disturbed host colonic epithelium and has an…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Regular and adequate levels of physical exercise help protect against several diseases and all-cause mortality. One of the mechanisms that has been gaining increasing attention in relation to how exercise impacts health outcomes is the favorable modification of the human gut microbiota. Although research in this field is still scarce, previous animal and human research findings showed that exercise can…

Stéphane Schneider
Professor Stéphane Schneider heads the Nutritional Support Unit in the Gastroenterology and Nutrition Department Archet University Hospital in Nice (France). He is also head of the Nice University Hospital’s food-nutrition liaison committee. Dr. Schneider is vice-president of the French-Speaking Society for Clinical Nutrition and Metabolism (SFNEP), and chairs the Educational and Clinical Practice Committee of the European Society for Clinical Nutrition and Metabolism (ESPEN). Three years after receiving his M.D. in Gastroenterology from the University of Nice Sophia-Antipolis, he became an assistant Professor and later a full Professor of Nutrition. He is also certified by the European Board of Gastroenterology and Hepatology. He obtained a Master of Science from the University of Paris VII, and a Ph.D. in nutrition from the University Paul Cezanne, as well as a CME Diploma from Harvard Medical School. His main research interests are intestinal failure and the effects of aging and chronic diseases on nutritional status. He has published 188 articles in peer-reviewed scientific journals, with an h index of 37. His goal is to help understand better the role of the intestinal ecosystem, as well as the effects of different forms of bacteriotherapy, in digestive and non-digestive disorders featuring dysbiosis.

Regular and adequate levels of physical exercise help protect against several diseases and all-cause mortality. One of the mechanisms that has been gaining increasing attention in relation to how exercise impacts health outcomes is the favorable modification of the human gut microbiota. Although research in this field is still scarce, previous animal and human research findings showed that exercise can…

Stéphane Schneider
Professor Stéphane Schneider heads the Nutritional Support Unit in the Gastroenterology and Nutrition Department Archet University Hospital in Nice (France). He is also head of the Nice University Hospital’s food-nutrition liaison committee. Dr. Schneider is vice-president of the French-Speaking Society for Clinical Nutrition and Metabolism (SFNEP), and chairs the Educational and Clinical Practice Committee of the European Society for Clinical Nutrition and Metabolism (ESPEN). Three years after receiving his M.D. in Gastroenterology from the University of Nice Sophia-Antipolis, he became an assistant Professor and later a full Professor of Nutrition. He is also certified by the European Board of Gastroenterology and Hepatology. He obtained a Master of Science from the University of Paris VII, and a Ph.D. in nutrition from the University Paul Cezanne, as well as a CME Diploma from Harvard Medical School. His main research interests are intestinal failure and the effects of aging and chronic diseases on nutritional status. He has published 188 articles in peer-reviewed scientific journals, with an h index of 37. His goal is to help understand better the role of the intestinal ecosystem, as well as the effects of different forms of bacteriotherapy, in digestive and non-digestive disorders featuring dysbiosis.

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

In microbiome research, many mechanistic insights are enabled through the use of animal models. A new paper co-led by Andy Wullaert in Belgium and Kathy McCoy in Switzerland addresses a major question about the use of animal models and the conclusions drawn from experiments that are not rigorously designed. Although it is well known that gut microbiota is important in…

Hervé Blottière
Research Director at INRA, the French National Research Institute for Agricultural and Food Research, Hervé Blottière presently heads a research laboratory studying the Human Intestinal Ecosystem within the MICALIS institute “Food and Gut Microbiology for Human Health”. He is Scientific Director of the MetaGenoPolis initiative, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments, where he has set up a robotic platform to allow high throughput screenings. He is also involved in ANR, the French National Research Agency, and the EU funded projects on Human Gut Microbiota and Health: MetaHIT, Cross-Talk and MetaCardis. Hervé Blottière obtained a PhD in Tumor Immunology from the University of Nantes (France) in 1989, and spent two years at the Wistar Institute (Philadelphia, U.S.A.). His main research interest is the Functional Metagenomics approach to study host-microbiota cross-talk. He has published >135 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the symbiosis between gut microbiota and its host and to decipher the mechanisms of interaction between intestinal bacteria and human mucosal cells at the molecular level. Finding these molecular mediators will provide target for manipulation or therapeutics tools to restore symbiosis in chronic diseases.

In microbiome research, many mechanistic insights are enabled through the use of animal models. A new paper co-led by Andy Wullaert in Belgium and Kathy McCoy in Switzerland addresses a major question about the use of animal models and the conclusions drawn from experiments that are not rigorously designed. Although it is well known that gut microbiota is important in…

Hervé Blottière
Research Director at INRA, the French National Research Institute for Agricultural and Food Research, Hervé Blottière presently heads a research laboratory studying the Human Intestinal Ecosystem within the MICALIS institute “Food and Gut Microbiology for Human Health”. He is Scientific Director of the MetaGenoPolis initiative, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments, where he has set up a robotic platform to allow high throughput screenings. He is also involved in ANR, the French National Research Agency, and the EU funded projects on Human Gut Microbiota and Health: MetaHIT, Cross-Talk and MetaCardis. Hervé Blottière obtained a PhD in Tumor Immunology from the University of Nantes (France) in 1989, and spent two years at the Wistar Institute (Philadelphia, U.S.A.). His main research interest is the Functional Metagenomics approach to study host-microbiota cross-talk. He has published >135 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the symbiosis between gut microbiota and its host and to decipher the mechanisms of interaction between intestinal bacteria and human mucosal cells at the molecular level. Finding these molecular mediators will provide target for manipulation or therapeutics tools to restore symbiosis in chronic diseases.

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team

Many questions arise when it comes to probiotics and gut microbiota. By what mechanisms of action can probiotics affect host health? What is the role of probiotics in preventing healthcare-associated infections? Do probiotics affect the intestinal barrier? The Gut Microbiota for Health publishing team has asked a selection of world-leading experts to weigh in on the answers, and we're pleased…

GMFH Editing Team
GMFH Editing Team