Tag Archives: Inflammation

Changes in the gut microbiota are involved in both homeostatic and inflammatory immune responses. T regulatory (Treg) immune cells tolerate diverse bacterial communities, whereas inflammatory conditions activate T effector (Teff) immune cells to react against the body’s own commensal microbiota. However, little is known regarding the role of commensal bacteria in inducing Teff cells during inflammation. A new study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Changes in the gut microbiota are involved in both homeostatic and inflammatory immune responses. T regulatory (Treg) immune cells tolerate diverse bacterial communities, whereas inflammatory conditions activate T effector (Teff) immune cells to react against the body’s own commensal microbiota. However, little is known regarding the role of commensal bacteria in inducing Teff cells during inflammation. A new study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Bacteria are responsive to the environment within the mammalian gut. Scientists have long desired to harness bacteria to detect disease or therapeutically influence the gut environment, but to date, synthetic genetic circuits in bacteria have proven susceptible to mutation and unpredictable function when they colonize the gut for an extended period of time. New work, led by Pamela Silver of…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Bacteria are responsive to the environment within the mammalian gut. Scientists have long desired to harness bacteria to detect disease or therapeutically influence the gut environment, but to date, synthetic genetic circuits in bacteria have proven susceptible to mutation and unpredictable function when they colonize the gut for an extended period of time. New work, led by Pamela Silver of…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Previous research has shown that the severity of immunodeficiency in human immunodeficiency virus (HIV) infection is related to changes in both the gut virome and bacterial microbiome. Although microbiota-targeted interventions are considered nowadays a potential therapeutic strategy for HIV-infected subjects, little data is available regarding the efficacy of those interventions in humans. A new double-blind, randomised, placebo-controlled trial, led by…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the severity of immunodeficiency in human immunodeficiency virus (HIV) infection is related to changes in both the gut virome and bacterial microbiome. Although microbiota-targeted interventions are considered nowadays a potential therapeutic strategy for HIV-infected subjects, little data is available regarding the efficacy of those interventions in humans. A new double-blind, randomised, placebo-controlled trial, led by…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Non-steroidal anti-inflammatory drugs (NSAIDs) -including aspirin, ibuprofen, naproxen, indomethacin, and piroxicam, among others- constitute one of the most frequently prescribed types of drugs that often cause mucosal lesions, not only in the stomach/duodenum, but also in the small intestine. Although several novel treatments have been explored to prevent or reduce NSAID-induced intestinal lesions (i.e., gastrointestinal-sparing NSAIDs, anti-ulcer drugs, anti-secretory agents,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Non-steroidal anti-inflammatory drugs (NSAIDs) -including aspirin, ibuprofen, naproxen, indomethacin, and piroxicam, among others- constitute one of the most frequently prescribed types of drugs that often cause mucosal lesions, not only in the stomach/duodenum, but also in the small intestine. Although several novel treatments have been explored to prevent or reduce NSAID-induced intestinal lesions (i.e., gastrointestinal-sparing NSAIDs, anti-ulcer drugs, anti-secretory agents,…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The aging process has been previously related to increased levels of inflammatory mediators such as cytokines and acute phase proteins in the bloodstream and tissues and to a perturbed gut microbiota. However, the underlying causes of age-associated inflammation remain unclear and it is not known whether this association is correlative or whether the gut microbiota is a cause of age-associated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The aging process has been previously related to increased levels of inflammatory mediators such as cytokines and acute phase proteins in the bloodstream and tissues and to a perturbed gut microbiota. However, the underlying causes of age-associated inflammation remain unclear and it is not known whether this association is correlative or whether the gut microbiota is a cause of age-associated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that gut microbiota dysbiosis may be involved in the pathogenesis of ankylosing spondylitis (AS), which is a chronic inflammatory disease that mainly affects the sacroiliac joints and spine. However, the implications it could have for both local and systemic immune responses in AS has not yet been explored. A recent study, led by Dr. Giovanni Triolo…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that gut microbiota dysbiosis may be involved in the pathogenesis of ankylosing spondylitis (AS), which is a chronic inflammatory disease that mainly affects the sacroiliac joints and spine. However, the implications it could have for both local and systemic immune responses in AS has not yet been explored. A recent study, led by Dr. Giovanni Triolo…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Fast food, gut microbes, sweet drinks, desk jobs: over the years, obesity has been blamed on many things. A Time-Life book on food and nutrition from 1967 implicated—among other things—cars. "The automobile has almost eliminated walking," write the authors. "This decrease in exercise, which reduces the requirement for calories, has not always been accompanied by a corresponding decrease in appetite."…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Fast food, gut microbes, sweet drinks, desk jobs: over the years, obesity has been blamed on many things. A Time-Life book on food and nutrition from 1967 implicated—among other things—cars. "The automobile has almost eliminated walking," write the authors. "This decrease in exercise, which reduces the requirement for calories, has not always been accompanied by a corresponding decrease in appetite."…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

“Forever young, I want to be forever young” sang the band Alphaville back in the eighties. In what looks like a paradox, we all want to live to an older age, to celebrate as many birthdays as possible, but at the same time we all want to stay young. No wonder: getting older is often linked to diseases and to…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

“Forever young, I want to be forever young” sang the band Alphaville back in the eighties. In what looks like a paradox, we all want to live to an older age, to celebrate as many birthdays as possible, but at the same time we all want to stay young. No wonder: getting older is often linked to diseases and to…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Celiac disease (CeD) is a complex immune mediated disorder that is triggered by abnormal immune responses to the dietary protein gluten, which is found in grains like wheat, barley, and rye. Normally, immune tolerance to dietary proteins prevents inflammatory immune responses from developing. However, in those with CeD, the presence of HLA susceptibility genes plus unknown environmental or immune triggers…

Heather Galipeau
Heather Galipeau is a Research Associate at McMaster University (Canada) where she is researching dietary and microbial interactions in celiac disease and inflammatory bowel disease. She obtained her PhD in 2015 from McMaster University in Elena Verdu’s lab, during which she found that the small intestinal microbial background influences the degree of immuno-pathology triggered by dietary antigens, such as gluten.

Dietary fibre is a key nutrient for optimizing gut health through fermentation by commensal microbiota in the colon. The vast majority of studies that support the health benefits of dietary fibre are observational, whereas little evidence from interventional studies is available and mechanisms involved in their effects on gut microbiota and immune response are poorly understood. A recent study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Dietary fibre is a key nutrient for optimizing gut health through fermentation by commensal microbiota in the colon. The vast majority of studies that support the health benefits of dietary fibre are observational, whereas little evidence from interventional studies is available and mechanisms involved in their effects on gut microbiota and immune response are poorly understood. A recent study, led…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados