Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, affecting more than 10% of the population, with the highest impact in women. Although its origin is still unknown, reduced gut microbial diversity could be involved in its development.
Gut dysbiosis and gastrointestinal complaints do not ameliorate after weight gain in anorexia nervosa patients
25 Jul 2016by Paul Enck
A recent study, led by Dr. John Penders, from the Department of Medical Microbiology at Maastricht University Medical Centre (The Netherlands), has found that gut dysbiosis and gastrointestinal complaints in anorexia nervosa patients do not recover after weight gain and/or normalisation of eating behaviour.
Gut microbiota changes may be responsible for depressive-like behaviours in mice through alterations in host metabolism
29 Jun 2016by Paul Enck
A recent study, led by Dr. Peng Xie from the Chongqing Medical University in China, has demonstrated that intestinal ‘dysbiosis’ may have a causal role in the development of depressive-like behaviours in mice through altering host metabolism.
A recent study, led by Dr. Claire Steves, a clinical research fellow from the Department of Twin Research & Genetic Epidemiology, King’s College London, identified several associations between host frailty and gut microbiota diversity, which might offer potential targets for intervention to strengthen healthy ageing.
Gestational diabetes mellitus (GDM) is one of the most frequent metabolic complications of pregnancy and its prevalence is up to 12% in developed countries. Nowadays, several studies are investigating new therapies for glucose control that may complement diet, exercise, and pharmacological therapies.
A recent study, led by Dr. Andrew S. Neish from the Department of Pathology and Laboratory Medicine at Emory University School of Medicine in Atlanta, found that Akkermansia muciniphila and other anaerobic bacteria may promote gut healing in mice.
What was the hottest topic in gut microbiota science this year? Many experts would say it was the study of interactions between gut microbiota and the immune system.
Gut microbiota and Immunity: A selection of content from the Gut Microbiota for Health Experts Exchange 2015
19 Jan 2016by Paul Enck
We are pleased to introduce another issue of our « Best of » series! What was the hottest topic in gut microbiota science this year? Many experts would say it was the study of interactions between gut microbiota and the immune system.
Research shows that host-microbe interactions can regulate immune and metabolic pathways. Here, Fu and colleagues investigated the connection between the microbiota and selected risk factors for cardiovascular disease in humans: abnormal blood lipid levels and high body mass.
Authors of this paper attempted a meta-analysis of 56 studies on single-strain and multi-strain probiotics for the treatment of IBS, but trials were so heterogeneous when it came to probiotic concentration, duration of treatment, and methodology, that the meta-analysis was abandoned.
