Video introduction to the work of the Gut Microbiota & Health Section of ESNM

2025 has been a productive year in gut microbiome research, spanning metabolic health, neurogastroenterology, immune modulation, and precision nutrition. In this ‘Year in Review’ article, the GMFH editing team describes their pick of the top GMFH-covered advances in 2025, outlining their impact in the clinical setting and implications for current and future research.

The definition of a prebiotic has evolved from a focus on colonic fiber to a complex ecological strategy. This article traces the concept's 30-year journey, highlighting the shift from non-digestible carbohydrates to the latest expert recommendations.

Cardiovascular diseases remain one of the most pressing public health concerns, demanding innovative research to identify novel causes. A recent Nature study reported that imidazole propionate made by gut bacteria contributes to atherosclerosis development, supporting its potential role as a biomarker of subclinical disease.