Introduction to the 2nd GMFH World Summit 2013

While diet is a major determinant of the human gut microbiome, little is known about diet-microbiome associations at species-level resolution. New findings from the Human Phenotype Project found species-level, food-specific associations validated at population scale that might guide personalized nutrition.

Digestive symptoms with an impact on quality of life (QoL) affect one in four adults in the general population worldwide who do not qualify for a diagnosis of a Disorder of Gut-Brain Interaction (DGBI). Recent research suggests this ‘sub-diagnostic’ group demands additional investigation and might benefit from targeted interventions, including dietary interventions.

The European regulatory landscape for microbiome-based therapies is rapidly evolving. New frameworks like the SoHO Regulation aim to harmonize safety, quality, and access across countries. This article explores the current challenges, opportunities, and expert perspectives shaping the field.