Gut microbiota is the human body's most complex, diverse and numerous ecosystem of all, particularly in the caecum, where the density of microorganisms is the highest.
Exposure to viral and bacterial infections early in life, especially in the setting of certain genetic predispositions, may increase an individual’s risk for developing food sensitivities.
Human-origin probiotic-cocktail inhibits the growth of uropathogenic bacteria and increases production of SCFAs
8 Oct 2018by Megan Mouw
Researchers have developed a new probiotic-cocktail of infant-gut origin that modulates the gut microbiota of mice (in-vivo) and human feces (ex-vivo) by increasing native production of SCFAs.
New GMFH “best of” document on gut microbiota & short-chain fatty acids
9 Mar 2017by GMFH Editing Team
How do the gut microbiota exert their effects in the intestinal tract and throughout the rest of the body?
Building a resilient immune system: Interview with Prof. Philip Calder (Part 1)
2 Nov 2016by Kristina Campbell
In the traditional view of your immune system, your body is a fortress that needs to be defended.
The role of short-chain fatty acids in driving obesity: Should we blame acetate?
5 Aug 2016by Patrice D. Cani
In a recent paper by Perry et al., researchers describe an investigation into the putative mechanisms by which gut microbiota alterations may lead to obesity, insulin resistance, and metabolic syndrome. Authors describe increased production of acetate by altered gut microbiota in rats. They link this to activation of the parasympathetic nervous system, increased glucose-stimulated insulin secretion, higher ghrelin secretion, hyperphagia, and obesity. Thus, they point to increased acetate production as a driver of metabolic syndrome.