Dietary fibers, known to regulate intestinal inflammation and gut barrier functions, have been avoided by patients with inflammatory bowel diseases (IBD) to avoid flare-ups. However, recent findings suggest that if fiber type, patient immunological condition, and the fermentative ability of the gut microbiota are taken into account, they could be beneficial and prevent relapses.
Restricting dietary fiber is a common advice for people living with inflammatory bowel disease. New research shows that not all fibers work the same and their impact on intestinal inflammation and gut barrier function depend on the type of fiber, individual immune status and the fermentative capacity of their gut microbes.
Study identifies a role for bacterial proteases in Crohn’s disease
26 Jun 2023by Amber Hann, Heather Galipeau
Inflammatory bowel disease is a chronic remitting and relapsing condition that causes severe inflammation of the intestines and disabling bowel symptoms. It affects millions of lives globally, and although alterations in the gut microbiome have been associated with IBD, precise mechanisms remain incompletely understood. New research from McMaster University now implicates bacterial proteases in Crohn’s disease.
Which dietary components should be promoted, and which ones should be limited in inflammatory bowel disease?
19 May 2023by GMFH Editing Team
What to eat or not to eat as a means of reducing IBD symptoms is one of the main queries a patient might have following diagnosis. Although there is no simple answer and dietary changes are not a substitute for medical therapy, to help consider this question, we have prepared a new infographic on the dietary components to promote and limit in patients with IBD.
The role of the gut mycobiota in influencing the immune system and inflammation-related diseases
12 Jan 2023by Andreu Prados
Gut fungi found in the lower gastrointestinal tract can influence the host immune system just like the bacterial microbiota. This article focuses on the role of the gut mycobiota in immune system homeostasis and its relevance for host health.
Long-term diet may affect the inflammatory effects of the gut microbiome more than specific foods alone
8 Sep 2021by Allison Clark
The purpose of the article is to uncover how dietary components and long-term dietary patterns interact with and influence gut microbiota composition and function and intestinal inflammation.
The inflammatory potential of diet is tied to Crohn’s disease risk but not to ulcerative colitis, suggests a new observational study
2 Nov 2020by Rene van den Wijngaard
Despite the fact that current guidelines for managing inflammatory bowel diseases do not devote attention to diet as a central element of treatment, there is an increasing amount of evidence that supports the role of diet in patients with IBD. A new nationwide cohort study shows the association between the level of inflammatory potential in diet and risk of Crohn’s disease.
Updated evidence on how diet may help in managing inflammatory bowel disease
14 Oct 2019by Paul Enck
An increasing amount of scientific evidence supports the role of diet in the management of IBD in its early stages. Here, Prof. Paul Enck updates preclinical and clinical research disentangling the contribution of diet as an ally in managing IBD through the gut microbiome.
Higher mucins production and an imbalanced gut microbiota found in Crohn´s Disease remission patients
26 Sep 2019by Allison Clark
Scientists struggle to understand why some gut bacteria are sensitive to antibiotics while a fraction of them survive treatment. New research in mice reveals that gut microbial metabolism alongside diet play a key role in modifying the extent of gut microbiome disruption in response to antibiotics.
New research sheds light on the effects of inflammatory bowel disease risk alleles on gut bacterial taxa
8 Apr 2019by GMFH Editing Team
Scientists struggle with elucidating how host and gut microbiome interact for shaping the genetic susceptibility of IBD. In 633 IBD patients, Harry Sokol and colleagues have found associations between genetic variants associated with a higher risk of IBD and the depletion of certain gut bacterial taxa.
