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2018 Gut Microbiota For Health World Summit Report

The relevance of gut microbiota-host interactions for

better health

Managing food-gut microbiota- nutritionists, dietitians...). Association (AGA). The 2018 edition
host interactions for better health The event was held on March 10 and of the Gut Microbiota for Health
and personalized strategies was 11 in Rome (Italy) and was organized World Summit was supported by
the central topic of the 2018 by the European Society of Danone, Biocodex and Sanofi.
Gut Microbiota for Health World Neurogastroenterology & Motility
Summit, which brought together (ESNM), the European Society
an international group of nearly 500 for Paediatric Gastroenterology,
scientists and healthcare professionals Hepatology and Nutrition (ESPGHAN)
(gastroenterologists, pediatricians, and the American Gastroenterological

What have we learnt from this 7th edition?

• Personalized microbiome-targeted • The gut microbiome interacts with potential gut microbiota targets for
therapies based on next-generation food components and educates immune managing gluten-related disorders.
probiotics and diet will improve responses in order to maintain mucosal
the management of nutrition- and homeostasis and immune tolerance • Through exploring host-diet-gut
immune-related diseases. in inflammatory bowel disease. microbiota interactions in animal models,
scientists are running experiments that
• The recently discovered ‘gut vascular • Gut microbiome-based strategies help with understanding why fiber is
barrier’ plays a fundamental role in may be useful for early diagnosis and good for us, yielding some important
avoiding indiscriminate trafficking of treatment of colorectal cancer. new clues about fiber’s role in human
bacteria from the gut into blood health.
circulation and is therefore a relevant • Emerging evidence highlights the role
target in patients with liver disease. of the gut microbiota in preventing and
treating obesity and the relevance of

Personalized microbiome-targeted therapies with diet and next-

generation probiotics

Clara Belzer (Wageningen, The
Netherlands) focused on recent
developments related to Akkermansia
muciniphila as a next-generation
probiotic, a term that refers to
commensal bacteria that are isolated
from human niches such as the gut,
skin or oral cavity and are considered
to have considerable potential with
regards to human health due to
their novel mechanisms of action.

Akkermansia, which was
first discovered in 2004,
could be the first official
next-generation probiotic to
treat obesity and metabolic Clara Belzer focused on recent developments related to Akkermansia muciniphila as a next-generation
syndrome based on the first probiotic.
human pilot study that has
shown its beneficial and safe Short-chain fatty acids (butyrate) important bacterium in metabolic
role for improving metabolic production probably plays a health.
health. significant role in explaining why You can find out more about the
Akkermansia muciniphila is an science behind the gut microbiota

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