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Restricting dietary fiber is a common advice for people living with inflammatory bowel disease. New research shows that not all fibers work the same and their impact on intestinal inflammation and gut barrier function depend on the type of fiber, individual immune status and the fermentative capacity of their gut microbes.

Inflammatory bowel disease is a chronic remitting and relapsing condition that causes severe inflammation of the intestines and disabling bowel symptoms. It affects millions of lives globally, and although alterations in the gut microbiome have been associated with IBD, precise mechanisms remain incompletely understood. New research from McMaster University now implicates bacterial proteases in Crohn’s disease.

What to eat or not to eat as a means of reducing IBD symptoms is one of the main queries a patient might have following diagnosis. Although there is no simple answer and dietary changes are not a substitute for medical therapy, to help consider this question, we have prepared a new infographic on the dietary components to promote and limit in patients with IBD.

While fecal microbiota transplants are recommended for multiple recurrent Clostridioides difficile infection, their use in clinical practice is hindered by a lack of regulation and understanding of the underlying ecological dynamics. This article covers major challenges for the treatment in transitioning from bench to bedside, from the scientific, clinical and regulatory perspectives (Part 6).