Prof. Jeffrey Gordon was invited to give a TED talk at the TEDxGatewayArch. His talk introduces the ideas of microbiota and microbiome, a new view to our connection to the microbial world as humans. He goes on detailing how our microbiome is for us a new way of considering our human evolution: it’s a part of evolution that goes much faster than that portrayed in our Homo sapiens genome, occuring at the level of our microbiome. It’s an opportunity to look at some of the most pressing health issues worldwide. In this perspective, Gordon offers to address the question of malnutrition and its possible connection with the gut microbiota. He describes how malnutrition is a complex dynamic, where gut microbiota represents one more factor. Is the microbiota causally related to risk for childhood undernutrition?