Interview with Dr. Stephen O’Keefe: How a low-fibre diet can increase colon cancer risk
Dr. Stephen J.D. O'Keefe is a Professor of Medicine at the University of Pittsburgh and a practicing gastroenterologist at the University of Pittsburgh Medical Center. His work focuses on 'nutritional gastroenterology' -- in particular, translational research that evaluates physiological and
Dr. Stephen J.D. O’Keefe is a Professor of Medicine at the University of Pittsburgh and a practicing gastroenterologist at the University of Pittsburgh Medical Center. His work focuses on ‘nutritional gastroenterology’ — in particular, translational research that evaluates physiological and pathophysiological responses to dietary intake.
Dr. O’Keefe gave a talk at Experimental Biology 2015 called, “Diet, Microbiota, and Microbial Metabolites in Rural Africans and African Americans“, where he presented data from his recent study.
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014. Find her on: Google • Twitter
Gut microbiome-targeted interventions are being explored as means of improving cognitive performance. A new meta-analysis of 22 randomized controlled studies has found no significant effect on improving cognition for probiotics, prebiotics and fermented foods, whether alone or used in combination.
Host lifestyle and diet are known to have a significant impact on the gut microbiome. A large observational study across 3400 individuals shows that, beyond interindividual variability, gut microbiome heterogeneity may play a role in individual responses to diet, lifestyle and medication.
How the enteric nervous system interacts with surrounding host and microbial cells is largely unknown, mainly due to the limitations of available methodologies for studying enteric neurons. A recent study provides new insights into enteric nervous system cells from both the mouse and human intestine.