Gut Summit 2013: impressions from the third day

Long-term treatment of functional dyspepsia with proton-pump inhibitors can alter the gut microbiome. A new pilot randomized, double-blind, placebo-controlled trial suggests the potential of spore-forming probiotics in patients with functional dyspepsia.

Our diet has a huge influence not only on gut microbiota composition but also on its functions. New findings show a fiber-enriched Mediterranean-like diet is well tolerated and influences microbial metabolism in just two weeks, despite no major changes in the core microbiota composition.

Scientists have discovered a fungus that delays wound healing in mice and is enriched in inflamed tissue from patients with Crohn’s disease. The findings, coupled with the discovery of an engineered yeast that suppresses inflammation in a mouse model of colitis, highlights the potential of studying fungi-host interactions in IBD.