Tag Archives: Gut microbiome

Gut microbiota dysbiosis has been associated with the onset of several immune- and metabolic-related disorders. The specific role of exogenous factors leading to dysbiosis is still under investigation, and the primary factors contributing to gut microbiome dysbiosis and ultimately to human disease are not clear. A new study, led by Dr. Boakai K. Robertson from the Department of Biological Sciences…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Gut microbiota dysbiosis has been associated with the onset of several immune- and metabolic-related disorders. The specific role of exogenous factors leading to dysbiosis is still under investigation, and the primary factors contributing to gut microbiome dysbiosis and ultimately to human disease are not clear. A new study, led by Dr. Boakai K. Robertson from the Department of Biological Sciences…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The intestinal epithelium is considered a novel target for addressing several acute and chronic gastrointestinal conditions. It also could have a potential role in targeting systemic diseases. It is an active component of the mucosal immune system. When considering the complex ecosystem combining the gastrointestinal epithelium, immune cells and resident microbiota, several probiotics like Lactobacillus fermentum exhibit immunoregulatory effects in…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The intestinal epithelium is considered a novel target for addressing several acute and chronic gastrointestinal conditions. It also could have a potential role in targeting systemic diseases. It is an active component of the mucosal immune system. When considering the complex ecosystem combining the gastrointestinal epithelium, immune cells and resident microbiota, several probiotics like Lactobacillus fermentum exhibit immunoregulatory effects in…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Previous research has found that the gut microbiome modulates both immune system development and gut homeostasis through its interaction with the host immune cells. Although both innate and adaptive humoral responses target distinct commensal bacteria via mucosal secretory immunoglobulin A (SIgA), little is known about whether secretory immunoglobulin M (SIgM) is also involved. A new study, led by Dr. Andrea…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has found that the gut microbiome modulates both immune system development and gut homeostasis through its interaction with the host immune cells. Although both innate and adaptive humoral responses target distinct commensal bacteria via mucosal secretory immunoglobulin A (SIgA), little is known about whether secretory immunoglobulin M (SIgM) is also involved. A new study, led by Dr. Andrea…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that a primary function of the gut microbiome is providing colonization resistance against many orally acquired pathogens; several exogenous factors, such as antibiotic treatments, could reduce host resistance to infections. The potential for manipulating the gut microbiome in the context of travellers’ health has not been previously explored in depth in a scientific review. A 2016…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that a primary function of the gut microbiome is providing colonization resistance against many orally acquired pathogens; several exogenous factors, such as antibiotic treatments, could reduce host resistance to infections. The potential for manipulating the gut microbiome in the context of travellers’ health has not been previously explored in depth in a scientific review. A 2016…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown the aging process and frailty may be associated with a perturbed gut microbiome in elderly people. Indeed, gut microbes could be a major driver of age-associated inflammation in mice, and specific microbial signatures of healthy aging have been previously reported in long-lived individuals. However, it is still unknown whether targeting gut microbes can be effective in…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown the aging process and frailty may be associated with a perturbed gut microbiome in elderly people. Indeed, gut microbes could be a major driver of age-associated inflammation in mice, and specific microbial signatures of healthy aging have been previously reported in long-lived individuals. However, it is still unknown whether targeting gut microbes can be effective in…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research from the two largest cohorts to date has shown that diet is one of the primary factors involved in gut microbiome variation among healthy individuals. Regarding bread type, little is known about how interpersonal variation affects clinical and microbiome-related responses. A new study, led by Dr. Avraham Levy, Dr Eran Elinav and Dr. Eran Segal from the Department…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research from the two largest cohorts to date has shown that diet is one of the primary factors involved in gut microbiome variation among healthy individuals. Regarding bread type, little is known about how interpersonal variation affects clinical and microbiome-related responses. A new study, led by Dr. Avraham Levy, Dr Eran Elinav and Dr. Eran Segal from the Department…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Constipation is a common condition that may result from altered gastrointestinal motility. Several factors appear relevant to gut motility: the gut luminal environment (including the gastrointestinal microbiota and fermentation), as well as factors related to the immune system, the enteric nervous system, and the central nervous system. Previous research has found associations between colonic transit time and aspects of patients’…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Faecal microbiota transplantation (FMT) is currently investigated as a novel treatment option for several chronic diseases related to gut dysbiosis with the strongest evidence for efficacy in the treatment of recurrent Clostridium difficile infection. Although clear reporting of FMT methodology is important to better understand and reproduce studies, reports of the methodological components of FMT interventions in clinical trials vary…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the severity of immunodeficiency in human immunodeficiency virus (HIV) infection is related to changes in both the gut virome and bacterial microbiome. Although microbiota-targeted interventions are considered nowadays a potential therapeutic strategy for HIV-infected subjects, little data is available regarding the efficacy of those interventions in humans. A new double-blind, randomised, placebo-controlled trial, led by…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous research has shown that the severity of immunodeficiency in human immunodeficiency virus (HIV) infection is related to changes in both the gut virome and bacterial microbiome. Although microbiota-targeted interventions are considered nowadays a potential therapeutic strategy for HIV-infected subjects, little data is available regarding the efficacy of those interventions in humans. A new double-blind, randomised, placebo-controlled trial, led by…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The human gut microbiota composition and metabolic activities are modulated by the diet, and reciprocally, host metabolism and metabolites also interact with the gut microbiota and diet, shaping a complex interacting network that relates to gut health. Several factors can influence the human gut microbiota, with diet being a very important one. Not only dietary pattern (vegetarian vs. omnivorous dietary…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The human gut microbiota composition and metabolic activities are modulated by the diet, and reciprocally, host metabolism and metabolites also interact with the gut microbiota and diet, shaping a complex interacting network that relates to gut health. Several factors can influence the human gut microbiota, with diet being a very important one. Not only dietary pattern (vegetarian vs. omnivorous dietary…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.