Tag Archives: Gut microbiome

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) and both environmental factors and genetic background affect its development. Due to the fact that MS is more prevalent in western countries, scientists have started to hypothesize that dietary habits could play an important role in MS risk. However, solid scientific data regarding the relationship between…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) and both environmental factors and genetic background affect its development. Due to the fact that MS is more prevalent in western countries, scientists have started to hypothesize that dietary habits could play an important role in MS risk. However, solid scientific data regarding the relationship between…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

New developments in genetics and metagenomics over the past 15 years have led scientists to produce an in-depth characterization of the composition and function of the gut microbiome as a novel organ in the close intersection between health and disease. As a result, the number of publications discussing the gut microbiota over the past five years represents more than 80%…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

New developments in genetics and metagenomics over the past 15 years have led scientists to produce an in-depth characterization of the composition and function of the gut microbiome as a novel organ in the close intersection between health and disease. As a result, the number of publications discussing the gut microbiota over the past five years represents more than 80%…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Tryptophan (Trp) is an essential amino acid and a precursor of several metabolites involved in key physiological processes. Metabolic pathways leading to serotonin (5-hydroxytryptamine) and other metabolites from Trp are under the direct or indirect control of the microbiota. A new review led by Prof. Harry Sokol, a gastroenterologist and researcher from the French National Institute for Agricultural Research (INRA)…

GMFH Editing Team
GMFH Editing Team

Tryptophan (Trp) is an essential amino acid and a precursor of several metabolites involved in key physiological processes. Metabolic pathways leading to serotonin (5-hydroxytryptamine) and other metabolites from Trp are under the direct or indirect control of the microbiota. A new review led by Prof. Harry Sokol, a gastroenterologist and researcher from the French National Institute for Agricultural Research (INRA)…

GMFH Editing Team
GMFH Editing Team

Previous data in animals and humans have shown the potential of manipulating the gut microbiome to modify emotional and cognitive behavior and brain function. For instance, Bifidobacterium longum 1714 has been tested for central effects in mice and humans, but studies assessing how probiotics may affect behavior and brain function in healthy volunteers are scarce. A new double-blind, placebo-controlled randomized…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Previous data in animals and humans have shown the potential of manipulating the gut microbiome to modify emotional and cognitive behavior and brain function. For instance, Bifidobacterium longum 1714 has been tested for central effects in mice and humans, but studies assessing how probiotics may affect behavior and brain function in healthy volunteers are scarce. A new double-blind, placebo-controlled randomized…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Previous experimental research has found that metabolomics can be used to monitor the impact of host diet on gut microbiota functionality. These data suggest that focusing on gut microbiota functionality may allow for a better characterization of the gut microbiota and its interaction with the host than only studying its composition. A new study, led by Dr. Tim Spector and…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Previous experimental research has found that metabolomics can be used to monitor the impact of host diet on gut microbiota functionality. These data suggest that focusing on gut microbiota functionality may allow for a better characterization of the gut microbiota and its interaction with the host than only studying its composition. A new study, led by Dr. Tim Spector and…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent research has found an association between colorectal cancer (CRC) and variations in the gut microbiome composition. Although mice research supports the theory that tumor development appears to be driven by interactions between the gut microbiome and host genomics, mechanisms involved in the crosstalk between colorectal carcinogenesis and the gut microbiome are still unknown. A new study, led by Prof.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent research has found an association between colorectal cancer (CRC) and variations in the gut microbiome composition. Although mice research supports the theory that tumor development appears to be driven by interactions between the gut microbiome and host genomics, mechanisms involved in the crosstalk between colorectal carcinogenesis and the gut microbiome are still unknown. A new study, led by Prof.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although gut microbiota profiles differ remarkably between healthy individuals, several features have been suggested to define a “healthy gut microbiome”. First of all, our gut microbiota can be understood, in many cases, to be redundant given that many bacterial species have similar functions. Furthermore, a healthy gut microbiome is temporally stable and resistant to perturbations and, over time, is more…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although gut microbiota profiles differ remarkably between healthy individuals, several features have been suggested to define a “healthy gut microbiome”. First of all, our gut microbiota can be understood, in many cases, to be redundant given that many bacterial species have similar functions. Furthermore, a healthy gut microbiome is temporally stable and resistant to perturbations and, over time, is more…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Eran Segal Computer Science Department, Weizmann Institute of Science Abstract: Accumulating evidence supports a causal role for the human gut microbiome in obesity, diabetes, metabolic disorders, cardiovascular disease, and numerous other conditions. I will present our research on the role of the human microbiome in health and disease, aimed at developing personalized medicine approaches that combine human genetics, microbiome, and nutrition. In one project, we tackled the…

GMFH Editing Team
GMFH Editing Team

Eran Segal Computer Science Department, Weizmann Institute of Science Abstract: Accumulating evidence supports a causal role for the human gut microbiome in obesity, diabetes, metabolic disorders, cardiovascular disease, and numerous other conditions. I will present our research on the role of the human microbiome in health and disease, aimed at developing personalized medicine approaches that combine human genetics, microbiome, and nutrition. In one project, we tackled the…

GMFH Editing Team
GMFH Editing Team

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Although intake of certain non-antibiotic drugs -antidiabetics such as metformin and acarbose, proton pump inhibitors, non-steroidal anti-inflammatory drugs, and second-generation antipsychotics, opioids and statins- that target human cells have been related to changes in the gut microbiome composition, little is known regarding the extent to which this happens for a broader range of drugs. A recent study, led by Dr.…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.