Tag Archives: Gut microbiome

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

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GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Life-threatening food allergies are constantly increasing in Westernized countries and alterations in the gut microbiome, especially in early life, could contribute to the rise in their prevalence. Although both a reduced bacterial diversity and an increased Enterobacteriaceae/Bacteroidaceae ratio in infancy have been associated with food sensitization, as well as increased levels of serum immunoglobulin E (IgE) in germ-free and antibiotics-treated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Life-threatening food allergies are constantly increasing in Westernized countries and alterations in the gut microbiome, especially in early life, could contribute to the rise in their prevalence. Although both a reduced bacterial diversity and an increased Enterobacteriaceae/Bacteroidaceae ratio in infancy have been associated with food sensitization, as well as increased levels of serum immunoglobulin E (IgE) in germ-free and antibiotics-treated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Different environmental factors may shape human gut microbiome variation. Although diet has a major influence on gut microbiome shifts within an individual, at population level, diet contributes little to gut microbiome variation. Although our gut microbiome might contribute to interindividual variability in response to diet, close monitoring of how temporal variation in diet alters gut microbiome composition and stability at…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Different environmental factors may shape human gut microbiome variation. Although diet has a major influence on gut microbiome shifts within an individual, at population level, diet contributes little to gut microbiome variation. Although our gut microbiome might contribute to interindividual variability in response to diet, close monitoring of how temporal variation in diet alters gut microbiome composition and stability at…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

The modification of the human gut microbiota’s composition and function is one of the plausible mechanisms that has just recently started being explored in relation to how exercise affects health. Although gut microbiome composition tends to show higher variability under environmental pressures, its diversity functionality tends to remain consistent within and across subjects. In professional athletes, however, little is known…

GMFH Editing Team
GMFH Editing Team

The modification of the human gut microbiota’s composition and function is one of the plausible mechanisms that has just recently started being explored in relation to how exercise affects health. Although gut microbiome composition tends to show higher variability under environmental pressures, its diversity functionality tends to remain consistent within and across subjects. In professional athletes, however, little is known…

GMFH Editing Team
GMFH Editing Team