Tag Archives: Gut microbiome

The gut microbiota is now believed to be a factor involved in the onset of cardiometabolic disorders such as obesity. In human and rat studies, the commensal* bacterium Akkermansia muciniphila- which is naturally present in large quantities in the gut microbiota of healthy people - has been gaining a lot of attention for its association with leanness and for producing…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

The gut microbiota is now believed to be a factor involved in the onset of cardiometabolic disorders such as obesity. In human and rat studies, the commensal* bacterium Akkermansia muciniphila- which is naturally present in large quantities in the gut microbiota of healthy people - has been gaining a lot of attention for its association with leanness and for producing…

Allison Clark
Allison Clark has a master in nutrition and health from Open University in Barcelona and a master in journalism. She is a freelance writer and nutritionist and has written various peer review papers about the role the gut microbiota plays in health, disease and endurance exercise performance. Allison is passionate about the role diet and the gut microbiota play in health and disease. Follow her on Twitter @Heal_your_Gut

The circadian rhythms (sleep-wake cycles)—integrated in the suprachiasmatic nuclei in the hypothalamus—can influence a wide range of host physiological functions, ranging from digestion to body temperature. Although previous data showed that our gut microbiota has its own circadian clocks and may respond to environmental light changes, the impact of circadian cycles on gut homeostasis is poorly understood. New research led…

GMFH Editing Team
GMFH Editing Team

The circadian rhythms (sleep-wake cycles)—integrated in the suprachiasmatic nuclei in the hypothalamus—can influence a wide range of host physiological functions, ranging from digestion to body temperature. Although previous data showed that our gut microbiota has its own circadian clocks and may respond to environmental light changes, the impact of circadian cycles on gut homeostasis is poorly understood. New research led…

GMFH Editing Team
GMFH Editing Team

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Traditionally, microbial communities that inhabit the human body and surrounding environments have been characterized through culturing on selective plates. However, this approach shows a low sensitivity and does not allow for exploring the unculturable fraction of the microbiome that may account for between 60% and 80% of the observable bacteria. Although culture-independent methods based on characterizing the 16S ribosomal ribonucleic…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

Parkinson’s disease is caused by the progressive loss of dopaminergic neurons and recent studies have widened the immune system and the gut microbiota's contribution to the disease. A new study in mice, led by researchers from the Université de Montréal and McGill University in Canada, shows the involvement of intestinal infections as a trigger in Parkinson’s disease through autoimmune mechanisms.…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

The fact some people respond to a drug treatment while for others the same treatment is totally ineffective may depend on our gut microbiota. In other words, after a drug is administered orally, it could either be absorbed into the bloodstream and metabolized by the liver, or it remains in the intestine where it can be metabolized by the gut…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Imbalances in the small intestinal microbiome can drive clinical consequences in the form of small intestinal bacterial overgrowth (SIBO), characterized by higher numbers of bacteria and a distribution more commonly associated with the colon. In recent times, SIBO has been recognized as a frequent cause of common gastrointestinal conditions that share risk factors such as maldigestion and malabsorption. Methods used…

GMFH Editing Team
GMFH Editing Team

Life-threatening food allergies are constantly increasing in Westernized countries and alterations in the gut microbiome, especially in early life, could contribute to the rise in their prevalence. Although both a reduced bacterial diversity and an increased Enterobacteriaceae/Bacteroidaceae ratio in infancy have been associated with food sensitization, as well as increased levels of serum immunoglobulin E (IgE) in germ-free and antibiotics-treated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Life-threatening food allergies are constantly increasing in Westernized countries and alterations in the gut microbiome, especially in early life, could contribute to the rise in their prevalence. Although both a reduced bacterial diversity and an increased Enterobacteriaceae/Bacteroidaceae ratio in infancy have been associated with food sensitization, as well as increased levels of serum immunoglobulin E (IgE) in germ-free and antibiotics-treated…

Andreu Prados
Andreu Prados holds a Bachelor of Science Degree in Pharmacy & Human Nutrition and Dietetics. Science writer specialised in gut microbiota and probiotics, working also as lecturer and consultant in nutrition and healthcare. Follow Andreu on Twitter @andreuprados

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

Maternal physiology and metabolism during pregnancy adjust so the fetus may grow healthy. As part of these changes, the gut microbiota evolves towards a pro-inflammatory profile, which contributes to a healthy pregnancy. Even so, the extent to which gut microbiota alterations induced by pregnancy and lactation may change autoimmune mechanisms that are involved in disease has not yet been explored.…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The functional metagenomic screening of the human gut microbiome gives us a better understanding of how microbial genes shape almost all aspects of physiology. Although an important number of microbial species have yet to be characterized, next generation approaches have increased the number of gut microorganism genomes that can be mapped. For instance, analysis of the gut metagenome has provided…

GMFH Editing Team
GMFH Editing Team

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The gut microbiota has become a new player in the onset and development of metabolic syndrome and its associated pathologies. One gut bacterium that has been positively associated with leanness in mice and humans is Akkermansia muciniphila, which is naturally present in the gut microbiota of healthy people. In 2017, our research team at UCLouvain (Belgium) found that a pasteurized…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.