Bacteria are responsive to the environment within the mammalian gut. Scientists have long desired to harness bacteria to detect disease or therapeutically influence the gut environment, but to date, synthetic genetic circuits in bacteria have proven susceptible to mutation and unpredictable function when they colonize the gut for an extended period of time. New work, led by Pamela Silver of…
Bacteria are responsive to the environment within the mammalian gut. Scientists have long desired to harness bacteria to detect disease or therapeutically influence the gut environment, but to date, synthetic genetic circuits in bacteria have proven susceptible to mutation and unpredictable function when they colonize the gut for an extended period of time. New work, led by Pamela Silver of…