Nutrition

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Research & Practice

When treating vulnerable populations with probiotics in research and clinical practice, the quality of probiotic products is important because the stakes are high. In October, 2014, for example, a preterm infant in Connecticut died of gastrointestinal mucormycosis that was caused by a contaminated probiotic product given in hospital. What lessons can clinicians and researchers take away from this situation?  …

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

When treating vulnerable populations with probiotics in research and clinical practice, the quality of probiotic products is important because the stakes are high. In October, 2014, for example, a preterm infant in Connecticut died of gastrointestinal mucormycosis that was caused by a contaminated probiotic product given in hospital. What lessons can clinicians and researchers take away from this situation?  …

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Prof. Iradj Sobhani is a physician in the Department of Gastroenterology at Assistance Publique-Hôpitaux de Paris, and a professor of medicine at University Paris-Est Créteil, in France. He is the director of the interdisciplinary research team Macbeth-EC2M3 (Microbiota and early colon cancer detection by using multimodal molecular markers). He and his co-authors recently published a paper in Molecular Systems Biology called 'Potential of fecal…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Prof. Iradj Sobhani is a physician in the Department of Gastroenterology at Assistance Publique-Hôpitaux de Paris, and a professor of medicine at University Paris-Est Créteil, in France. He is the director of the interdisciplinary research team Macbeth-EC2M3 (Microbiota and early colon cancer detection by using multimodal molecular markers). He and his co-authors recently published a paper in Molecular Systems Biology called 'Potential of fecal…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

We are pleased to introduce the first edition of our « Best of » series! In this first issue, you have at your fingertips the best way to get up-to-date on the area of gut microbiota, diet and nutrition. In this document, we’ve compiled a selected group of articles, summaries, and interviews from the last two years on our website,…

Elena Verdú
Dr. Verdu’s research has focused on the pathophysiology of inflammatory and functional gastrointestinal disorders. She undertook clinical research training at the University of Lausanne, Switzerland, where she studied the interaction between chronic infection with Helicobacter pylori and gastritis in humans and the possible therapeutic role of probiotic bacteria. Her PhD studies in the Institute of Microbiology and Gnotobiology at the Czech Academy of Science and University of Lausanne focused on the effect of bacterial antigens in animal models of inflammatory bowel disease. As a post-doctoral fellow at McMaster University she gained experience with animal models of gut functional diseases and investigated the mechanisms of action of probiotic bacteria. As a member of the Farncombe Family Digestive Health Research Institute at McMaster University, Dr. Verdu investigates host-microbial and dietary interactions in the context of celiac disease, irritable bowel syndrome and inflammatory bowel disease. She has been honored with the New Investigator Award (Canadian Celiac Association), the New Investigator Award (Functional Gut-Brain Research Group, USA) and the Campbell Research Award in celiac disease (Canadian Celiac Association). The American Gastroenterology Association and the Canadian Association of Gastroenterology have awarded her the “Master’s in Gastroenterology Award” for basic science and “Young Investigator’s Award”, respectively. She is Associate Professor at the Division of Gastroenterology, Dep. of Medicine at McMaster University and currently directs the Axenic Gnotobiotic Unit at McMaster.

We are pleased to introduce the first edition of our « Best of » series! In this first issue, you have at your fingertips the best way to get up-to-date on the area of gut microbiota, diet and nutrition. In this document, we’ve compiled a selected group of articles, summaries, and interviews from the last two years on our website,…

Elena Verdú
Dr. Verdu’s research has focused on the pathophysiology of inflammatory and functional gastrointestinal disorders. She undertook clinical research training at the University of Lausanne, Switzerland, where she studied the interaction between chronic infection with Helicobacter pylori and gastritis in humans and the possible therapeutic role of probiotic bacteria. Her PhD studies in the Institute of Microbiology and Gnotobiology at the Czech Academy of Science and University of Lausanne focused on the effect of bacterial antigens in animal models of inflammatory bowel disease. As a post-doctoral fellow at McMaster University she gained experience with animal models of gut functional diseases and investigated the mechanisms of action of probiotic bacteria. As a member of the Farncombe Family Digestive Health Research Institute at McMaster University, Dr. Verdu investigates host-microbial and dietary interactions in the context of celiac disease, irritable bowel syndrome and inflammatory bowel disease. She has been honored with the New Investigator Award (Canadian Celiac Association), the New Investigator Award (Functional Gut-Brain Research Group, USA) and the Campbell Research Award in celiac disease (Canadian Celiac Association). The American Gastroenterology Association and the Canadian Association of Gastroenterology have awarded her the “Master’s in Gastroenterology Award” for basic science and “Young Investigator’s Award”, respectively. She is Associate Professor at the Division of Gastroenterology, Dep. of Medicine at McMaster University and currently directs the Axenic Gnotobiotic Unit at McMaster.

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

In recent years, several studies reported a shift in the intestinal microbiota in humans and mice in response to high-fat diets. This shift is characterised by a reduction of Bacteroidetes and an increase of Firmicutes. The Erysipelotrichi, a bacterial class within the Firmicutes, was shown to be associated with symptoms of the metabolic syndrome. Furthermore, faecal transplantation transmitted the obese…

GMFH Editing Team
GMFH Editing Team

In recent years, several studies reported a shift in the intestinal microbiota in humans and mice in response to high-fat diets. This shift is characterised by a reduction of Bacteroidetes and an increase of Firmicutes. The Erysipelotrichi, a bacterial class within the Firmicutes, was shown to be associated with symptoms of the metabolic syndrome. Furthermore, faecal transplantation transmitted the obese…

GMFH Editing Team
GMFH Editing Team