Immune Health

News Watch

Researchers find new correlations between the gut microbiota and immune response genes in people with multiple sclerosis During the last 15 years, scientists have started to discover that the 100 trillion microorganisms living in our digestive tract –mostly in the colon- play a key role in different body functions, like digestion and training the immune system. What’s more, they have…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

Researchers find new correlations between the gut microbiota and immune response genes in people with multiple sclerosis During the last 15 years, scientists have started to discover that the 100 trillion microorganisms living in our digestive tract –mostly in the colon- play a key role in different body functions, like digestion and training the immune system. What’s more, they have…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

Babies are born with immature immune systems. Until now, it was believed that the birth process was the first opportunity for microorganisms from the mother to colonize the baby’s gut and, thus, to shape the immune system. Now, a team formed by German and Swiss scientists have discovered that this interaction with the baby’s immune system starts much earlier than…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

Babies are born with immature immune systems. Until now, it was believed that the birth process was the first opportunity for microorganisms from the mother to colonize the baby’s gut and, thus, to shape the immune system. Now, a team formed by German and Swiss scientists have discovered that this interaction with the baby’s immune system starts much earlier than…

Cristina Sáez
Cristina Saez is a freelance science journalist. She works for several media, for instance the Spanish newspaper La Vanguardia, where she coordinates the science section, Big Vang; as well as research centres and scientific societies. She has been awarded for her journalistic work, among others, with the Boehringer Ingelheim Award in Medical Journalism 2015. Follow Cristina on Twitter @saez_cristina

Thirty-three percent of people have a gene that predisposes them to celiac disease (CD), while only two to five percent of the population will receive a diagnosis of the condition. Elena Verdú, Associate Professor and researcher at McMaster University in Canada, wants to know why the unlucky minority end up with the disease. "We know that genes are necessary, but…

GMFH Editing Team
GMFH Editing Team

Thirty-three percent of people have a gene that predisposes them to celiac disease (CD), while only two to five percent of the population will receive a diagnosis of the condition. Elena Verdú, Associate Professor and researcher at McMaster University in Canada, wants to know why the unlucky minority end up with the disease. "We know that genes are necessary, but…

GMFH Editing Team
GMFH Editing Team

A baby’s diaper may not be the most pleasant thing to look at, but what it contains can provide doctors with a hint about whether that child may develop asthma later in life, thus allowing them to start treating him or her in order to prevent the disease. Researchers have found that four bacteria found in the faeces of a…

GMFH Editing Team
GMFH Editing Team

A baby’s diaper may not be the most pleasant thing to look at, but what it contains can provide doctors with a hint about whether that child may develop asthma later in life, thus allowing them to start treating him or her in order to prevent the disease. Researchers have found that four bacteria found in the faeces of a…

GMFH Editing Team
GMFH Editing Team

Martin J. Blaser, director of the Department of Medicine at New York University School of Medicine, is one of the world's greatest experts in the relationship between use and overuse of antibiotics and the gut microbiota. We were able to interview him during the 4th Gut Microbiota for Health World Summit and discover the biological cost of antibiotic overuse, what…

GMFH Editing Team
GMFH Editing Team

Martin J. Blaser, director of the Department of Medicine at New York University School of Medicine, is one of the world's greatest experts in the relationship between use and overuse of antibiotics and the gut microbiota. We were able to interview him during the 4th Gut Microbiota for Health World Summit and discover the biological cost of antibiotic overuse, what…

GMFH Editing Team
GMFH Editing Team

Research & Practice

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Recent observational data in infants (here; here) suggest a developmental origin for childhood atopy and subsequent asthma involving the gut microbiome perturbation and associated metabolic dysfunction in early life. However, little is known regarding gut microbiota maturation over the first year of life in infants at high risk for asthma and whether targeting the gut microbiome may modify disease risk.…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

The prevalence of childhood allergic diseases is increasing throughout the world. Although previous research (here; here) has found that gut microbial colonization dynamics differ between allergic and healthy infants, little is known regarding the extent to which specific changes in gut microbiota composition in early life could be used as potential biomarkers of later allergic disease, or could be used…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

The Gut Microbiota for Health publishing team is delighted to share the second summary document on the latest scientific work related to gut microbiota and probiotics! With gastrointestinal (GI) symptoms high in prevalence throughout the world, and with limited available therapeutic options for addressing functional GI disorders, is there a role for probiotics? This document covers human research that elucidates…

GMFH Editing Team
GMFH Editing Team

In microbiome research, many mechanistic insights are enabled through the use of animal models. A new paper co-led by Andy Wullaert in Belgium and Kathy McCoy in Switzerland addresses a major question about the use of animal models and the conclusions drawn from experiments that are not rigorously designed. Although it is well known that gut microbiota is important in…

Hervé Blottière
Research Director at INRA, the French National Research Institute for Agricultural and Food Research, Hervé Blottière presently heads a research laboratory studying the Human Intestinal Ecosystem within the MICALIS institute “Food and Gut Microbiology for Human Health”. He is Scientific Director of the MetaGenoPolis initiative, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments, where he has set up a robotic platform to allow high throughput screenings. He is also involved in ANR, the French National Research Agency, and the EU funded projects on Human Gut Microbiota and Health: MetaHIT, Cross-Talk and MetaCardis. Hervé Blottière obtained a PhD in Tumor Immunology from the University of Nantes (France) in 1989, and spent two years at the Wistar Institute (Philadelphia, U.S.A.). His main research interest is the Functional Metagenomics approach to study host-microbiota cross-talk. He has published >135 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the symbiosis between gut microbiota and its host and to decipher the mechanisms of interaction between intestinal bacteria and human mucosal cells at the molecular level. Finding these molecular mediators will provide target for manipulation or therapeutics tools to restore symbiosis in chronic diseases.

In microbiome research, many mechanistic insights are enabled through the use of animal models. A new paper co-led by Andy Wullaert in Belgium and Kathy McCoy in Switzerland addresses a major question about the use of animal models and the conclusions drawn from experiments that are not rigorously designed. Although it is well known that gut microbiota is important in…

Hervé Blottière
Research Director at INRA, the French National Research Institute for Agricultural and Food Research, Hervé Blottière presently heads a research laboratory studying the Human Intestinal Ecosystem within the MICALIS institute “Food and Gut Microbiology for Human Health”. He is Scientific Director of the MetaGenoPolis initiative, a platform of excellence dedicated to quantitative and functional metagenomics, funded by the French government Futures Investments, where he has set up a robotic platform to allow high throughput screenings. He is also involved in ANR, the French National Research Agency, and the EU funded projects on Human Gut Microbiota and Health: MetaHIT, Cross-Talk and MetaCardis. Hervé Blottière obtained a PhD in Tumor Immunology from the University of Nantes (France) in 1989, and spent two years at the Wistar Institute (Philadelphia, U.S.A.). His main research interest is the Functional Metagenomics approach to study host-microbiota cross-talk. He has published >135 publications in peer reviewed scientific journals. His goal is to provide a better understanding of the symbiosis between gut microbiota and its host and to decipher the mechanisms of interaction between intestinal bacteria and human mucosal cells at the molecular level. Finding these molecular mediators will provide target for manipulation or therapeutics tools to restore symbiosis in chronic diseases.

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team

Gut-related symptoms, including flatulence, bloating, heartburn, nausea, vomiting, constipation, diarrhoea, food intolerance, incontinence, and abdominal pain affect approximately one third of the general population, according to the World Gastroenterology Organisation. Among the functional gastrointestinal disorders (FGIDs) that are characterized by persistent and recurring GI symptoms, irritable bowel syndrome (IBS) affects around 11% of the population globally and can interfere with…

GMFH Editing Team
GMFH Editing Team