Gut Microbiota

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Research & Practice

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz

Using mice models, scientists from UCL and WUR found that Akkermansia muciniphila could have a role in reversing high-fat diet-induced metabolic disorders, in this study obesity and type-2 diabetes. The two first authors, Amandine Everard and Clara Belzer, having respectively a background in Pharmaceutical Sciences and Molecular Microbiology accepted to give us their feedback on their main findings.   1)…

GMFH Editing Team
GMFH Editing Team

Using mice models, scientists from UCL and WUR found that Akkermansia muciniphila could have a role in reversing high-fat diet-induced metabolic disorders, in this study obesity and type-2 diabetes. The two first authors, Amandine Everard and Clara Belzer, having respectively a background in Pharmaceutical Sciences and Molecular Microbiology accepted to give us their feedback on their main findings.   1)…

GMFH Editing Team
GMFH Editing Team

During the Biovision Forum 2013, you chaired the session on the Gut Microbiota and moderated a round table on the subject. What are the main messages coming out of this event?   FL: I think it was an excellent initiative that the Biovision Forum got interested in the microbiota and that the topic was in the spotlight. The forum has…

GMFH Editing Team
GMFH Editing Team

During the Biovision Forum 2013, you chaired the session on the Gut Microbiota and moderated a round table on the subject. What are the main messages coming out of this event?   FL: I think it was an excellent initiative that the Biovision Forum got interested in the microbiota and that the topic was in the spotlight. The forum has…

GMFH Editing Team
GMFH Editing Team

Can you tell us a little bit about you and how you got interested in Gut Microbiota?   FL: I was trained as a geneticist. As a PhD student (2000-2003), I worked in a lab that used the Drosophila fly  as a model for research. My scientific questions were on immunity (infection resistance, especially those of bacterial origin) in Bruno…

GMFH Editing Team
GMFH Editing Team

Can you tell us a little bit about you and how you got interested in Gut Microbiota?   FL: I was trained as a geneticist. As a PhD student (2000-2003), I worked in a lab that used the Drosophila fly  as a model for research. My scientific questions were on immunity (infection resistance, especially those of bacterial origin) in Bruno…

GMFH Editing Team
GMFH Editing Team

American journalist Michael Pollan shares his experience with the American Gut Project and gives a full overview on the human microbiome as we know it today. "Here were the names of the hundreds of bacterial species that call me home. In sheer numbers, these microbes and their genes dwarf us. It turns out that we are only 10 percent human:…

GMFH Editing Team
GMFH Editing Team

American journalist Michael Pollan shares his experience with the American Gut Project and gives a full overview on the human microbiome as we know it today. "Here were the names of the hundreds of bacterial species that call me home. In sheer numbers, these microbes and their genes dwarf us. It turns out that we are only 10 percent human:…

GMFH Editing Team
GMFH Editing Team