Gut Microbiota

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Research & Practice

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team

Stein and colleagues describe in their study, published in PLOS computational biology, how time series can help to study dynamics of the microbiota. Moreover, unlike usual cross sectional studies which lack a mechanistic understanding of the ecosystem's structure and its response to external perturbations, modelling dynamics can help to predict and recover the microbiota temporal dynamics. For example, they modeled…

GMFH Editing Team
GMFH Editing Team

Thirty organizations from fifteen countries are coming together to conduct gut microbiome research in a new project called MyNewGut. Professor Yolanda Sanz has been appointed MyNewGut's project coordinator and leads the project's human intervention trials on the gut microbiome's ability to metabolise nutrients and influence energy balance. She is a Professor of Research at the Institute of Agrochemistry and Food Technology (IATA) of the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Thirty organizations from fifteen countries are coming together to conduct gut microbiome research in a new project called MyNewGut. Professor Yolanda Sanz has been appointed MyNewGut's project coordinator and leads the project's human intervention trials on the gut microbiome's ability to metabolise nutrients and influence energy balance. She is a Professor of Research at the Institute of Agrochemistry and Food Technology (IATA) of the…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Lawrence and colleagues tracked two subjects' microbiota over a year, collecting 800 fecal and saliva samples associated with 10,000 longitudinal measurements. They first highlighted the evidence for long-term, overall community stability, as differences between individuals were much larger than variation within individuals. They found a small subset of highly abundant core taxa can be found within each stable period. Secondly, they…

GMFH Editing Team
GMFH Editing Team

Lawrence and colleagues tracked two subjects' microbiota over a year, collecting 800 fecal and saliva samples associated with 10,000 longitudinal measurements. They first highlighted the evidence for long-term, overall community stability, as differences between individuals were much larger than variation within individuals. They found a small subset of highly abundant core taxa can be found within each stable period. Secondly, they…

GMFH Editing Team
GMFH Editing Team