Category : Probiotics

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Below is the best of our Twitter coverage of the four sessions of the 'Probiotics Throughout the Lifespan' Symposium which was held in September at the Harvard Medical School. Session IA: Pregnancy Session IB: Neonatal Period Session II: Adult Period Session III: Older Adults All the tweets can be accessed on Twitter by searching the #hprobio14 hashtag. ----- Session IA: Pregnancy Moderator:…

GMFH Editing Team
GMFH Editing Team

Below is the best of our Twitter coverage of the four sessions of the 'Probiotics Throughout the Lifespan' Symposium which was held in September at the Harvard Medical School. Session IA: Pregnancy Session IB: Neonatal Period Session II: Adult Period Session III: Older Adults All the tweets can be accessed on Twitter by searching the #hprobio14 hashtag. ----- Session IA: Pregnancy Moderator:…

GMFH Editing Team
GMFH Editing Team

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Probiotics have a well-known definition that has been cited for over a decade: ‘Live microorganisms which when administered in adequate amounts confer a health benefit on the host’. Written in a 2001 joint report of the Food and Agriculture Organization of the United Nations and the World Health Organization (FAO/WHO), it is a definition that served well at the time,…

GMFH Editing Team
GMFH Editing Team

Probiotics have a well-known definition that has been cited for over a decade: ‘Live microorganisms which when administered in adequate amounts confer a health benefit on the host’. Written in a 2001 joint report of the Food and Agriculture Organization of the United Nations and the World Health Organization (FAO/WHO), it is a definition that served well at the time,…

GMFH Editing Team
GMFH Editing Team

A panel of scientific experts* assembled in London, UK, on October 23, 2013 to discuss the scope and appropriate use of the term ‘probiotic.’ The International Scientific Association for Probiotics and Prebiotics (ISAPP) organized the meeting to review the relevance of the 12-year-old FAO/WHO definition of probiotics: "Live microorganisms which when administered in adequate amounts confer a health benefit on…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

A panel of scientific experts* assembled in London, UK, on October 23, 2013 to discuss the scope and appropriate use of the term ‘probiotic.’ The International Scientific Association for Probiotics and Prebiotics (ISAPP) organized the meeting to review the relevance of the 12-year-old FAO/WHO definition of probiotics: "Live microorganisms which when administered in adequate amounts confer a health benefit on…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

In an article published online on June 24, 2014 in the Journal of Clinical Investigation, Zhongyi Chen and Lilu Guo, from the Vanderbilt University, Nashville, Tennessee, USA, showed that the administration of a modified bacteria expressing therapeutic factors in the gut microbiota could reduce food intake and obesity. By adding an engineered NAPE*-expressing E. coli Nissle 1917 strain in the drinking water of mice for 8 weeks,…

GMFH Editing Team
GMFH Editing Team

In an article published online on June 24, 2014 in the Journal of Clinical Investigation, Zhongyi Chen and Lilu Guo, from the Vanderbilt University, Nashville, Tennessee, USA, showed that the administration of a modified bacteria expressing therapeutic factors in the gut microbiota could reduce food intake and obesity. By adding an engineered NAPE*-expressing E. coli Nissle 1917 strain in the drinking water of mice for 8 weeks,…

GMFH Editing Team
GMFH Editing Team

A Nature Medicine paper by Hitesh S Deshmukh and colleagues from the Division of Neonatology, Childrens Hospital of Philadelphia, Pennsilvania, USA reports an important aspect to the use of antibiotics in the integrity of the immune system in the newborn. Neonatal colonization by microbes, which begins immediately after birth, is influenced by gestational age and the mother’s microbiota and is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

A Nature Medicine paper by Hitesh S Deshmukh and colleagues from the Division of Neonatology, Childrens Hospital of Philadelphia, Pennsilvania, USA reports an important aspect to the use of antibiotics in the integrity of the immune system in the newborn. Neonatal colonization by microbes, which begins immediately after birth, is influenced by gestational age and the mother’s microbiota and is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

At the occasion of the "New therapies in coeliac disease" conference hosted by Columbia University in New-York on March 20, 2014, Dr. Elena Verdú, our expert in Nutrition, is sharing with us the last trends in research in the field of Coeliac Disease (CeD), introducing the idea of a role of probiotics in the treatment of CeD. Presence of intestinal dysbiosis…

Elena Verdú
Dr. Verdu’s research has focused on the pathophysiology of inflammatory and functional gastrointestinal disorders. She undertook clinical research training at the University of Lausanne, Switzerland, where she studied the interaction between chronic infection with Helicobacter pylori and gastritis in humans and the possible therapeutic role of probiotic bacteria. Her PhD studies in the Institute of Microbiology and Gnotobiology at the Czech Academy of Science and University of Lausanne focused on the effect of bacterial antigens in animal models of inflammatory bowel disease. As a post-doctoral fellow at McMaster University she gained experience with animal models of gut functional diseases and investigated the mechanisms of action of probiotic bacteria. As a member of the Farncombe Family Digestive Health Research Institute at McMaster University, Dr. Verdu investigates host-microbial and dietary interactions in the context of celiac disease, irritable bowel syndrome and inflammatory bowel disease. She has been honored with the New Investigator Award (Canadian Celiac Association), the New Investigator Award (Functional Gut-Brain Research Group, USA) and the Campbell Research Award in celiac disease (Canadian Celiac Association). The American Gastroenterology Association and the Canadian Association of Gastroenterology have awarded her the “Master’s in Gastroenterology Award” for basic science and “Young Investigator’s Award”, respectively. She is Associate Professor at the Division of Gastroenterology, Dep. of Medicine at McMaster University and currently directs the Axenic Gnotobiotic Unit at McMaster.

At the occasion of the "New therapies in coeliac disease" conference hosted by Columbia University in New-York on March 20, 2014, Dr. Elena Verdú, our expert in Nutrition, is sharing with us the last trends in research in the field of Coeliac Disease (CeD), introducing the idea of a role of probiotics in the treatment of CeD. Presence of intestinal dysbiosis…

Elena Verdú
Dr. Verdu’s research has focused on the pathophysiology of inflammatory and functional gastrointestinal disorders. She undertook clinical research training at the University of Lausanne, Switzerland, where she studied the interaction between chronic infection with Helicobacter pylori and gastritis in humans and the possible therapeutic role of probiotic bacteria. Her PhD studies in the Institute of Microbiology and Gnotobiology at the Czech Academy of Science and University of Lausanne focused on the effect of bacterial antigens in animal models of inflammatory bowel disease. As a post-doctoral fellow at McMaster University she gained experience with animal models of gut functional diseases and investigated the mechanisms of action of probiotic bacteria. As a member of the Farncombe Family Digestive Health Research Institute at McMaster University, Dr. Verdu investigates host-microbial and dietary interactions in the context of celiac disease, irritable bowel syndrome and inflammatory bowel disease. She has been honored with the New Investigator Award (Canadian Celiac Association), the New Investigator Award (Functional Gut-Brain Research Group, USA) and the Campbell Research Award in celiac disease (Canadian Celiac Association). The American Gastroenterology Association and the Canadian Association of Gastroenterology have awarded her the “Master’s in Gastroenterology Award” for basic science and “Young Investigator’s Award”, respectively. She is Associate Professor at the Division of Gastroenterology, Dep. of Medicine at McMaster University and currently directs the Axenic Gnotobiotic Unit at McMaster.