Category : Probiotics

With a greater public awareness of probiotics, patients may ask health professionals to recommend a probiotic suitable for their needs. Products vary on many parameters: genus, species, alphanumeric designation, number of live bacteria, blend of probiotic strains, and non-active ingredients. How do professionals assess the relevance of each product available for a particular patient? A new Canadian mobile app was…

GMFH Editing Team
GMFH Editing Team

With a greater public awareness of probiotics, patients may ask health professionals to recommend a probiotic suitable for their needs. Products vary on many parameters: genus, species, alphanumeric designation, number of live bacteria, blend of probiotic strains, and non-active ingredients. How do professionals assess the relevance of each product available for a particular patient? A new Canadian mobile app was…

GMFH Editing Team
GMFH Editing Team

The Inflammatory Bowel Diseases (IBDs), which include Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract. The etiology of IBDs is not known yet but it is certainly multi-factorial and it includes genetic as well as environmental factors. Over the last years it has become clear, however, that IBD develops in genetically…

Marcello Romeo
Dr Marcello Romeo is currently at PHD School in Molecular and Experimental Medicine at Department of Experimental Biomedicine and Clinical Neuroscience at University of Palermo (Italy). His main research interest is the molecular assessment of the Human Intestinal Microbiota in health and disease and investigation of the molecular cross-talk between intestinal bacteria and Heat Shock Proteins in colon mucosa of Inflammatory Bowel Disease and Colon Cancer.

The Inflammatory Bowel Diseases (IBDs), which include Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract. The etiology of IBDs is not known yet but it is certainly multi-factorial and it includes genetic as well as environmental factors. Over the last years it has become clear, however, that IBD develops in genetically…

Marcello Romeo
Dr Marcello Romeo is currently at PHD School in Molecular and Experimental Medicine at Department of Experimental Biomedicine and Clinical Neuroscience at University of Palermo (Italy). His main research interest is the molecular assessment of the Human Intestinal Microbiota in health and disease and investigation of the molecular cross-talk between intestinal bacteria and Heat Shock Proteins in colon mucosa of Inflammatory Bowel Disease and Colon Cancer.

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Dr. Erika Isolauri is a professor of paediatrics at the University of Turku, and chief physician at the Department of Paediatrics at Turku University Hospital in Finland. At the 2014 Harvard Probiotics Symposium she presented a talk entitled Probiotic Use During Pregnancy for Protection Against Childhood Diseases. She sat down with Gut Microbiota for Health after the event to describe…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Below is the best of our Twitter coverage of the four sessions of the 'Probiotics Throughout the Lifespan' Symposium which was held in September at the Harvard Medical School. Session IA: Pregnancy Session IB: Neonatal Period Session II: Adult Period Session III: Older Adults All the tweets can be accessed on Twitter by searching the #hprobio14 hashtag. ----- Session IA: Pregnancy Moderator:…

GMFH Editing Team
GMFH Editing Team

Below is the best of our Twitter coverage of the four sessions of the 'Probiotics Throughout the Lifespan' Symposium which was held in September at the Harvard Medical School. Session IA: Pregnancy Session IB: Neonatal Period Session II: Adult Period Session III: Older Adults All the tweets can be accessed on Twitter by searching the #hprobio14 hashtag. ----- Session IA: Pregnancy Moderator:…

GMFH Editing Team
GMFH Editing Team

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

In this contribution, GMFH board member Mary Ellen Sanders analyzes one of our recent website selections:  Veiga et al. (2014) Changes of the human gut microbiome induced by a fermented milk product. Probiotics are a promising means to manipulate the microbiome, but there is little evidence that they can do this by changing the microbiota composition. Yes, the genus or…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Probiotics have a well-known definition that has been cited for over a decade: ‘Live microorganisms which when administered in adequate amounts confer a health benefit on the host’. Written in a 2001 joint report of the Food and Agriculture Organization of the United Nations and the World Health Organization (FAO/WHO), it is a definition that served well at the time,…

GMFH Editing Team
GMFH Editing Team

Probiotics have a well-known definition that has been cited for over a decade: ‘Live microorganisms which when administered in adequate amounts confer a health benefit on the host’. Written in a 2001 joint report of the Food and Agriculture Organization of the United Nations and the World Health Organization (FAO/WHO), it is a definition that served well at the time,…

GMFH Editing Team
GMFH Editing Team

A panel of scientific experts* assembled in London, UK, on October 23, 2013 to discuss the scope and appropriate use of the term ‘probiotic.’ The International Scientific Association for Probiotics and Prebiotics (ISAPP) organized the meeting to review the relevance of the 12-year-old FAO/WHO definition of probiotics: "Live microorganisms which when administered in adequate amounts confer a health benefit on…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

A panel of scientific experts* assembled in London, UK, on October 23, 2013 to discuss the scope and appropriate use of the term ‘probiotic.’ The International Scientific Association for Probiotics and Prebiotics (ISAPP) organized the meeting to review the relevance of the 12-year-old FAO/WHO definition of probiotics: "Live microorganisms which when administered in adequate amounts confer a health benefit on…

Mary Ellen Sanders
Mary Ellen Sanders is a consultant in the area of probiotic microbiology, with special expertise on paths to scientific substantiation of probiotic product label claims. Dr. Sanders served as the founding president of the International Scientific Association for Probiotics and Prebiotics (ISAPP) and is currently the organization’s Director of Scientific Affairs/ Executive Officer. This international, non-profit association of academic and industrial scientists is dedicated to advancing the science of probiotics and prebiotics (www.isapp.net). Through numerous written, oral and video pieces, including a website, www.usprobiotics.org, she strives to provide objective, evidence-based information on probiotics for consumers and professionals. Key activities include: Panels to determine GRAS status of probiotic strains ; member of the American Gastroenterological Association Scientific Advisory Board for AGA Center for Gut Microbiome Research and Education ; World Gastroenterology Organisation Committee preparing practice guidelines for the use of probiotics and prebiotics for GI indications (2008, 2011, 2014) ; working group convened by the FAO/WHO that developed guidelines for probiotics (2002).

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

Using a stress model in animals, Da Silva and colleagues induced gut hyperpermeability and visceral hypersensitivity as well as a shift in O-glycosylation of mucins, associated with flattening and loss of the mucus layer cohesive properties. The probiotic L. farciminis bound to intestinal Muc2 prevented stress-induced functional alterations and changes in mucin O-glycosylation and mucus physical properties and restored epithelial…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

In an article published online on June 24, 2014 in the Journal of Clinical Investigation, Zhongyi Chen and Lilu Guo, from the Vanderbilt University, Nashville, Tennessee, USA, showed that the administration of a modified bacteria expressing therapeutic factors in the gut microbiota could reduce food intake and obesity. By adding an engineered NAPE*-expressing E. coli Nissle 1917 strain in the drinking water of mice for 8 weeks,…

GMFH Editing Team
GMFH Editing Team

In an article published online on June 24, 2014 in the Journal of Clinical Investigation, Zhongyi Chen and Lilu Guo, from the Vanderbilt University, Nashville, Tennessee, USA, showed that the administration of a modified bacteria expressing therapeutic factors in the gut microbiota could reduce food intake and obesity. By adding an engineered NAPE*-expressing E. coli Nissle 1917 strain in the drinking water of mice for 8 weeks,…

GMFH Editing Team
GMFH Editing Team