Category : Research & Practice

Filipe De Vadder is a molecular biologist in Gilles Mithieux group and published recently an important article in Cell journal which illustrate how gut microbiota fermentation product could impact neural communication. He accepted for GMFH to give us some highlights. 1) What is the context of this study? Dietary fiber has long been known for its beneficial effects on health,…

GMFH Editing Team
GMFH Editing Team

Filipe De Vadder is a molecular biologist in Gilles Mithieux group and published recently an important article in Cell journal which illustrate how gut microbiota fermentation product could impact neural communication. He accepted for GMFH to give us some highlights. 1) What is the context of this study? Dietary fiber has long been known for its beneficial effects on health,…

GMFH Editing Team
GMFH Editing Team

Until now, the role of specific gut microbes in shaping body composition was poorly understood. A new study carried out by researchers in the Washington University School of Medicine in St. Louis clarified how diet and gut microbes interact to affect weight gain.   In this study, Ridaura and colleagues transplanted intact uncultured fecal microbiota from adult female twin pairs…

GMFH Editing Team
GMFH Editing Team

Until now, the role of specific gut microbes in shaping body composition was poorly understood. A new study carried out by researchers in the Washington University School of Medicine in St. Louis clarified how diet and gut microbes interact to affect weight gain.   In this study, Ridaura and colleagues transplanted intact uncultured fecal microbiota from adult female twin pairs…

GMFH Editing Team
GMFH Editing Team

Machiels et al. recently described that the composition of the faecal microbiota of patients suffering from ulcerative colitis differs from that of healthy individuals: they found a reduction in two well-known butyrate-producing bacteria of the Firmicutes phylum, Roseburia hominis and Faecalibacterium prausnitzii. This has been confirmed in other studies. The dysbiosis found in the two inflammatory bowel diseases (IBD) i.e. Crohn’s…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.

Machiels et al. recently described that the composition of the faecal microbiota of patients suffering from ulcerative colitis differs from that of healthy individuals: they found a reduction in two well-known butyrate-producing bacteria of the Firmicutes phylum, Roseburia hominis and Faecalibacterium prausnitzii. This has been confirmed in other studies. The dysbiosis found in the two inflammatory bowel diseases (IBD) i.e. Crohn’s…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.

Science’s editors named “Our Microbes, Our Health” as runner-up for Breakthrough of the Year 2013.   This Science Magazine “News” article highlighted some studies on gut microbiota, published in several magazines in 2013. It represented a good collection of some of the most important findings involving microbioma and health. Among the selected topics, we could find studies connecting gut microbiota…

GMFH Editing Team
GMFH Editing Team

Science’s editors named “Our Microbes, Our Health” as runner-up for Breakthrough of the Year 2013.   This Science Magazine “News” article highlighted some studies on gut microbiota, published in several magazines in 2013. It represented a good collection of some of the most important findings involving microbioma and health. Among the selected topics, we could find studies connecting gut microbiota…

GMFH Editing Team
GMFH Editing Team

Here's the report of the “Gut microbiota and management of digestive health” symposium that was held during the UEG Week 2013 in Berlin, Germany, on the 13th of October 2013. Download the report.  

GMFH Editing Team
GMFH Editing Team

Here's the report of the “Gut microbiota and management of digestive health” symposium that was held during the UEG Week 2013 in Berlin, Germany, on the 13th of October 2013. Download the report.  

GMFH Editing Team
GMFH Editing Team

One year at a glance is the compilation of the most relevant and popular content on gut microbiota as published on the GMFH website.   The topic is rapidly growing across all fields of expertise and questions it raises are endless. It seems that hardly a day goes without gut microbiota being related to the health status (enterotypes, second genotype, ageing),…

GMFH Editing Team
GMFH Editing Team

One year at a glance is the compilation of the most relevant and popular content on gut microbiota as published on the GMFH website.   The topic is rapidly growing across all fields of expertise and questions it raises are endless. It seems that hardly a day goes without gut microbiota being related to the health status (enterotypes, second genotype, ageing),…

GMFH Editing Team
GMFH Editing Team

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team

The gut mobile metagenome comprises mobile genetic element (MGE) like bacterial viruses, known as bacteriophages. Although few studies showed that there is high interpersonal variation, little is known about how the gut microbiota react under phage attacks itselfs. Reyes and colleagues used gnobiotic mouse to improve the understanding of viral-bacterial dynamics. They built an artificial microbiota using 15 bacterial sequenced…

GMFH Editing Team
GMFH Editing Team

The gut mobile metagenome comprises mobile genetic element (MGE) like bacterial viruses, known as bacteriophages. Although few studies showed that there is high interpersonal variation, little is known about how the gut microbiota react under phage attacks itselfs. Reyes and colleagues used gnobiotic mouse to improve the understanding of viral-bacterial dynamics. They built an artificial microbiota using 15 bacterial sequenced…

GMFH Editing Team
GMFH Editing Team

(Berlin, October 16, 2013) Clinicians with gastrointestinal (GI) patients often wish – and are asked by their patients – to recommend specific probiotics. However, a clear and accessible evidence-based reference guide on the role and effectiveness of specific probiotics and their clinical use for managing particular lower gastrointestinal problems has been lacking so far. Now a new reference guide, which…

GMFH Editing Team
GMFH Editing Team

(Berlin, October 16, 2013) Clinicians with gastrointestinal (GI) patients often wish – and are asked by their patients – to recommend specific probiotics. However, a clear and accessible evidence-based reference guide on the role and effectiveness of specific probiotics and their clinical use for managing particular lower gastrointestinal problems has been lacking so far. Now a new reference guide, which…

GMFH Editing Team
GMFH Editing Team