Previous research has shown that adults with irritable bowel syndrome (IBS) who adopt a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet show an improvement in symptoms within 2 days. Would the low FODMAP diet have the same effect in childhood IBS? Does the gut microbiota predict the success of the diet in children who respond to this dietary intervention?
Gut Microbiota Research & Practice is a section dedicated to promoting knowledge-sharing and debate among researchers, scientists and healthcare professionals. You will find a selection of discussions about articles from scientific literature as well as other content including interviews with experts, event reports, and special publications.
In this Nature Medicine news article, Roxanne Khamsi reports on research around the world showing the microbiome exerts an influence on the human immune system. If scientists knew how to control the key process of inflammation, they could profoundly influence the course of disorders such as inflammatory bowel disease, heart disease, and liver disease.
Fermented foods are not included in the recently revised ISAPP definition of probiotics, since the bacteria they contain are uncharacterized. But scientists are nevertheless studying how these foods may affect health, including brain function.
Pawnobes’: Cultivated commensal microbes that impact host phenotype
21 Jul 2015by GMFH Editing Team
Thousands of years ago, humans went beyond hunting and gathering and began purposefully selecting and growing the most beneficial plants; what we know as the agricultural revolution was born. Is it possible that cultivating the microbiome would create a comparable paradigm shift?
FMT for ulcerative colitis holds promise despite discontinued Canadian trial, says Moayyedi
20 Jul 2015by Kristina Campbell
Dr. Paul Moayyedi, a gastroenterologist and researcher at McMaster University in Hamilton, Canada, was the first author of a study published earlier this year that investigated fecal microbiota transplantation (FMT) as a way to induce remission in patients with ulcerative colitis (UC). (See the study summary here.)
After intestinal anastomosis -- resection and reconnection of intestinal segments -- the intestine sometimes fails to heal. Leakage, peritonitis, and sepsis can result: in other words, anastomotic leak. The underlying cause of this complication is unknown, but evidence is growing that intestinal microbes play a role.
Digestive Disease Week AGA Symposium: Celiac Disease and Gut Microbiota
20 Jul 2015by Stefan Jellbauer
Quality and quantity of gluten, maturity of gut functions influencing antigen trafficking and handling (e.g. pattern recognition receptors and barrier function) and changes in microbiome composition are factors that contribute to the pathogenesis of the disease.
#ICTRHN2015 Report Part Two: From gut microbiota science to clinical implications
16 Jul 2015by Amandine Everard
The Third International Congress of Translational Research in Human Nutrition took place in Clermont-Ferrand, France, on June 26 & 27, 2015.
The human stomach has its own microbiota, but it receives less scientific attention than the intestines -- perhaps because acidic conditions, peristalsis, and the gastric mucus layer interfere with bacterial colonization. Nevertheless, characterizing the healthy gastric microbiota may be important
#ICTRHN2015 Report: From microbiota-host crosstalk to gut inflammation
15 Jul 2015by Amandine Everard
The Third International Congress of Translational Research in Human Nutrition (#ICTRHN2015) took place in Clermont-Ferrand, France, on June 26 & 27, 2015.
