Liping Zhao and colleagues, in their recent paper on a dietary intervention for simple and genetic obesity, discussed evidence for the existence of gut microbiota 'guilds': bacterial genomes within the gut ecosystem that responded to the dietary intervention as a group.

Previous research has shown that adults with irritable bowel syndrome (IBS) who adopt a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet show an improvement in symptoms within 2 days. Would the low FODMAP diet have the same effect in childhood IBS? Does the gut microbiota predict the success of the diet in children who respond to this dietary intervention?

In this Nature Medicine news article, Roxanne Khamsi reports on research around the world showing the microbiome exerts an influence on the human immune system. If scientists knew how to control the key process of inflammation, they could profoundly influence the course of disorders such as inflammatory bowel disease, heart disease, and liver disease.

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