Category : Food & Ingredients

Researchers from Israel recently published in Nature how NAS [Non-caloric artificial sweeteners] affect glucose tolerance. In an initial experiment, researchers found mice that consumed water, glucose, or sucrose had comparable glucose tolerance curves, but all 3 mouse groups consuming NAS (either saccharin, sucralose, or aspartame) developed marked glucose intolerance. They focused on saccharin for the next series of experiments, since…

GMFH Editing Team
GMFH Editing Team

Researchers from Israel recently published in Nature how NAS [Non-caloric artificial sweeteners] affect glucose tolerance. In an initial experiment, researchers found mice that consumed water, glucose, or sucrose had comparable glucose tolerance curves, but all 3 mouse groups consuming NAS (either saccharin, sucralose, or aspartame) developed marked glucose intolerance. They focused on saccharin for the next series of experiments, since…

GMFH Editing Team
GMFH Editing Team

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Patrick Veiga and MetaHIT colleagues tested how fermented milks product could modulate microbiota. Using a metagenomics approach, they found that the abundance of unknown species increased in the gut when patients took the fermented milk product. Having access to the functional content, authors found that those species had the functional potential to produce butyrate. Patrick Veiga accepted to give us…

GMFH Editing Team
GMFH Editing Team

Marion Leclerc is a French microbiologist working at INRA  (the French National Institute for Agricultural Research) Jouy-en-Josas Centre. She spoke with Gut Microbiota for Health about her various areas of research.   What research are you doing on functional characterization of the gut microbiota? I am now [cooperating] with Patricia Lepage... we have different projects where we try to go from known…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Marion Leclerc is a French microbiologist working at INRA  (the French National Institute for Agricultural Research) Jouy-en-Josas Centre. She spoke with Gut Microbiota for Health about her various areas of research.   What research are you doing on functional characterization of the gut microbiota? I am now [cooperating] with Patricia Lepage... we have different projects where we try to go from known…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Lawrence and colleagues tracked two subjects' microbiota over a year, collecting 800 fecal and saliva samples associated with 10,000 longitudinal measurements. They first highlighted the evidence for long-term, overall community stability, as differences between individuals were much larger than variation within individuals. They found a small subset of highly abundant core taxa can be found within each stable period. Secondly, they…

GMFH Editing Team
GMFH Editing Team

Lawrence and colleagues tracked two subjects' microbiota over a year, collecting 800 fecal and saliva samples associated with 10,000 longitudinal measurements. They first highlighted the evidence for long-term, overall community stability, as differences between individuals were much larger than variation within individuals. They found a small subset of highly abundant core taxa can be found within each stable period. Secondly, they…

GMFH Editing Team
GMFH Editing Team

This article is a collaboration of representatives from academia, medicine, and industry who came together at a workshop during the International Scientific Association for Probiotics and Prebiotics (ISAPP) held in Cork, Ireland in October, 2012. The goal of the workshop was to assess evidence on the link between the microbiome and under-nutrition, focusing specifically on probiotic and prebiotic treatments. Participants hoped…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

This article is a collaboration of representatives from academia, medicine, and industry who came together at a workshop during the International Scientific Association for Probiotics and Prebiotics (ISAPP) held in Cork, Ireland in October, 2012. The goal of the workshop was to assess evidence on the link between the microbiome and under-nutrition, focusing specifically on probiotic and prebiotic treatments. Participants hoped…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Prof. Patrice Cani, of Belgium’s Université catholique de Louvain, is involved in the Metabolism and Nutrition research group of the Louvain Drug Research Institute. He investigates the role of the gut microbiota in the development of metabolic disorders: obesity, type 2 diabetes and low-grade inflammation. He aims to uncover the mechanisms involved in the gut-to-liver and in the gut-to-adipose tissue…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Prof. Patrice Cani, of Belgium’s Université catholique de Louvain, is involved in the Metabolism and Nutrition research group of the Louvain Drug Research Institute. He investigates the role of the gut microbiota in the development of metabolic disorders: obesity, type 2 diabetes and low-grade inflammation. He aims to uncover the mechanisms involved in the gut-to-liver and in the gut-to-adipose tissue…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

This basic research sought to better understand how soluble dietary fibers exert their beneficial effect on body weight and glucose control. The researchers show that two short-chain fatty acids, which are produced by fermentation of soluble fiber by gut bacteria, activate intestinal gluconeogenesis (IGN) gene expression through different, but complementary, mechanisms. One of the mechanisms activates IGN gene expression through a…

GMFH Editing Team
GMFH Editing Team

This basic research sought to better understand how soluble dietary fibers exert their beneficial effect on body weight and glucose control. The researchers show that two short-chain fatty acids, which are produced by fermentation of soluble fiber by gut bacteria, activate intestinal gluconeogenesis (IGN) gene expression through different, but complementary, mechanisms. One of the mechanisms activates IGN gene expression through a…

GMFH Editing Team
GMFH Editing Team

Filipe De Vadder is a molecular biologist in Gilles Mithieux group and published recently an important article in Cell journal which illustrate how gut microbiota fermentation product could impact neural communication. He accepted for GMFH to give us some highlights. 1) What is the context of this study? Dietary fiber has long been known for its beneficial effects on health,…

GMFH Editing Team
GMFH Editing Team

Filipe De Vadder is a molecular biologist in Gilles Mithieux group and published recently an important article in Cell journal which illustrate how gut microbiota fermentation product could impact neural communication. He accepted for GMFH to give us some highlights. 1) What is the context of this study? Dietary fiber has long been known for its beneficial effects on health,…

GMFH Editing Team
GMFH Editing Team

Machiels et al. recently described that the composition of the faecal microbiota of patients suffering from ulcerative colitis differs from that of healthy individuals: they found a reduction in two well-known butyrate-producing bacteria of the Firmicutes phylum, Roseburia hominis and Faecalibacterium prausnitzii. This has been confirmed in other studies. The dysbiosis found in the two inflammatory bowel diseases (IBD) i.e. Crohn’s…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.

Machiels et al. recently described that the composition of the faecal microbiota of patients suffering from ulcerative colitis differs from that of healthy individuals: they found a reduction in two well-known butyrate-producing bacteria of the Firmicutes phylum, Roseburia hominis and Faecalibacterium prausnitzii. This has been confirmed in other studies. The dysbiosis found in the two inflammatory bowel diseases (IBD) i.e. Crohn’s…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.