Researchers from Israel recently published in Nature how NAS [Non-caloric artificial sweeteners] affect glucose tolerance. In an initial experiment, researchers found mice that consumed water, glucose, or sucrose had comparable glucose tolerance curves, but all 3 mouse groups consuming NAS
Akkermansia muciniphila and Faecalibacterium prausnitzii differentially affect host transcriptional response: focus on a powerful tool to study host-microbe interactions
21 Aug 2014by Patrice D. Cani
Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii
Interview with Dr. Karine Clément on human genes and microbial genes in obesity
12 Aug 2014by Kristina Campbell
Karine Clément is a physician and a professor at Paris 6 Pierre et Marie Curie University in Paris and director of an INSERM team. She is also the director of ICAN (Institute of Cardiometabolism and Nutrition),Pitié-Salpêtrière hospital, which focuses on care,
In an article published online on June 24, 2014 in the Journal of Clinical Investigation, Zhongyi Chen and Lilu Guo, from the Vanderbilt University, Nashville, Tennessee, USA, showed that the administration of a modified bacteria expressing therapeutic factors in the gut microbiota could reduce
Prof. Patrice Cani, of Belgium’s Université catholique de Louvain, is involved in the Metabolism and Nutrition research group of the Louvain Drug Research Institute. He investigates the role of the gut microbiota in the development of metabolic disorders: obesity, type
Following our video series from the Gut Microbiota for Health World Summit 2014, here is the interview of Prof. Max Nieuwdorp on the connection between metabolic syndrome and obesity to the gut microbiota. https://www.gutmicrobiotaforhealth.com/videos/gmfh2014-interviews/Max-Nieuwdorp.mp4
“Model Systems to Understand Microbiota-host Interactions” conference in Durham university: feedback from Dr François Leulier
30 Apr 2014by François Leulier
The workshop entitled "Model Systems to Understand Microbiota-host Interactions" took place in Durham University on April 23-24th 2014. It has been organized by David Weinkove and sponsored by the BBSRC and Durham Biophysical Sciences Institute. The main purpose
After a residency in Internal Medicine and fellowship in Endocrinology at the AMC-UvA and a postdoctoral fellowship on glycobiology at UC San Diego (prof. Jeff Esko, department of Cellular and Molecular Medicine), Dr Nieuwdorp started his own translational research group
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
10 Feb 2014by GMFH Editing Team
The beneficial effects of dietary fibers on gastrointestinal inflammatory disorders has been widely studied. However, the consequences of dietary fiber intake on inflammation outside of the intestine, for instance, in the lung has been poorly documented. Here, Trompette and colleagues
Transplanting fecal microbiota from twins discordant for obesity differentially affects metabolic activities in mice
6 Sep 2013by Patrice D. Cani
The team of Jeffrey Gordon (Ridaura et al. Science 2013) published that the phenotype of obesity (increased adiposity) of an obese twin in a discordant twin pair is transmissible. In other words, they found that mice receiving an obese twin’s