Category : Metabolic Conditions

The workshop entitled "Model Systems to Understand Microbiota-host Interactions" took place in Durham University on April 23-24th 2014. It has been organized by David Weinkove and sponsored by the BBSRC and Durham Biophysical Sciences Institute.     The main purpose of the workshop was to bring together people that use model systems to understand microbiota-host interactions with their "end users",…

François Leulier
Principal Investigator of the Functional genomics of host-intestinal bacteria interactions group at #igfl (@LeulierLab).#Drosophila #microbiota #probiotics

The workshop entitled "Model Systems to Understand Microbiota-host Interactions" took place in Durham University on April 23-24th 2014. It has been organized by David Weinkove and sponsored by the BBSRC and Durham Biophysical Sciences Institute.     The main purpose of the workshop was to bring together people that use model systems to understand microbiota-host interactions with their "end users",…

François Leulier
Principal Investigator of the Functional genomics of host-intestinal bacteria interactions group at #igfl (@LeulierLab).#Drosophila #microbiota #probiotics

After a residency in Internal Medicine and fellowship in Endocrinology at the AMC-UvA and a postdoctoral fellowship on glycobiology at UC San Diego (prof. Jeff Esko, department of Cellular and Molecular Medicine), Dr Nieuwdorp started his own translational research group (currently 10 PhD students, 1 postdoctoral fellow, 1 technician) focusing on translational research aimed at dissecting the causal role of…

GMFH Editing Team
GMFH Editing Team

After a residency in Internal Medicine and fellowship in Endocrinology at the AMC-UvA and a postdoctoral fellowship on glycobiology at UC San Diego (prof. Jeff Esko, department of Cellular and Molecular Medicine), Dr Nieuwdorp started his own translational research group (currently 10 PhD students, 1 postdoctoral fellow, 1 technician) focusing on translational research aimed at dissecting the causal role of…

GMFH Editing Team
GMFH Editing Team

The beneficial effects of dietary fibers on gastrointestinal inflammatory disorders has been widely studied. However, the consequences of dietary fiber intake on inflammation outside of the intestine, for instance, in the lung has been poorly documented. Here, Trompette and colleagues showed that dietary fiber content changed the composition of the gut and lung microbiota in mice, in particular by altering…

GMFH Editing Team
GMFH Editing Team

The beneficial effects of dietary fibers on gastrointestinal inflammatory disorders has been widely studied. However, the consequences of dietary fiber intake on inflammation outside of the intestine, for instance, in the lung has been poorly documented. Here, Trompette and colleagues showed that dietary fiber content changed the composition of the gut and lung microbiota in mice, in particular by altering…

GMFH Editing Team
GMFH Editing Team

The team of Jeffrey Gordon (Ridaura et al. Science 2013) published that the phenotype of obesity (increased adiposity) of an obese twin in a discordant twin pair is transmissible. In other words, they found that mice receiving an obese twin’s fecal microbiota display a greater fat mass than the mice receiving lean twin’s gut microbes. Cohousing is widely used in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The team of Jeffrey Gordon (Ridaura et al. Science 2013) published that the phenotype of obesity (increased adiposity) of an obese twin in a discordant twin pair is transmissible. In other words, they found that mice receiving an obese twin’s fecal microbiota display a greater fat mass than the mice receiving lean twin’s gut microbes. Cohousing is widely used in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Some individuals seem to be more susceptible to develop obesity or are more resistant to weight loss during dietary restriction. Emerging evidence suggest that few bacterial genera (i.e., Bifidobacterium, Lactobacillus, Faecalibacterium and Akkermansia) are inversely associated with obesity, metabolic inflammation and related metabolic disorders in both human and rodent studies. However so far, a common integrative factor is still being…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Some individuals seem to be more susceptible to develop obesity or are more resistant to weight loss during dietary restriction. Emerging evidence suggest that few bacterial genera (i.e., Bifidobacterium, Lactobacillus, Faecalibacterium and Akkermansia) are inversely associated with obesity, metabolic inflammation and related metabolic disorders in both human and rodent studies. However so far, a common integrative factor is still being…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz

The intestinal microbiota is known to modulate bioavailability and efficacy of endogenous compounds, nutrients or drugs, with large interindividual variations. The least conserved fraction of our microbiota may hence explain a stratification of the human population in converters and non converters for numerous compounds. As an example, the reduction of cholesterol to coprostanol is only active in a fraction of…

Fernando Aspiroz

Using mice models, scientists from UCL and WUR found that Akkermansia muciniphila could have a role in reversing high-fat diet-induced metabolic disorders, in this study obesity and type-2 diabetes. The two first authors, Amandine Everard and Clara Belzer, having respectively a background in Pharmaceutical Sciences and Molecular Microbiology accepted to give us their feedback on their main findings.   1)…

GMFH Editing Team
GMFH Editing Team

Using mice models, scientists from UCL and WUR found that Akkermansia muciniphila could have a role in reversing high-fat diet-induced metabolic disorders, in this study obesity and type-2 diabetes. The two first authors, Amandine Everard and Clara Belzer, having respectively a background in Pharmaceutical Sciences and Molecular Microbiology accepted to give us their feedback on their main findings.   1)…

GMFH Editing Team
GMFH Editing Team

Can you tell us about your experience prior to Enterome?   PR: I worked for 14 years as a general practitioner, a family doctor and even as a country doctor. I think it’s worth mentioning because my interest for gut microbiota is based on my experience as a field doctor. This is what I call the “earthly approach to medicine”.…

GMFH Editing Team
GMFH Editing Team

Can you tell us about your experience prior to Enterome?   PR: I worked for 14 years as a general practitioner, a family doctor and even as a country doctor. I think it’s worth mentioning because my interest for gut microbiota is based on my experience as a field doctor. This is what I call the “earthly approach to medicine”.…

GMFH Editing Team
GMFH Editing Team

Dr Alice Liou, first author of a recent article published in Science Translational Medicine,  gives us some clarification about gastric bypass effect on intestinal microbiota.   1) What is your background ?   I am a gastrointestinal physiologist with an interest in understanding the contributions of the gastrointestinal tract in regulating energy balance and metabolism. I received my DVM (veterinary)…

GMFH Editing Team
GMFH Editing Team

Dr Alice Liou, first author of a recent article published in Science Translational Medicine,  gives us some clarification about gastric bypass effect on intestinal microbiota.   1) What is your background ?   I am a gastrointestinal physiologist with an interest in understanding the contributions of the gastrointestinal tract in regulating energy balance and metabolism. I received my DVM (veterinary)…

GMFH Editing Team
GMFH Editing Team

Scientists from Brussels University noticed recently in a recent published article that enterotypes could be found also in mice model whatever the genetic background. Although genetic and environmental factor have to be taken in account during any experiment with mice, authors also said that mice enterotypes have also to be controlled. The two first authors of this study, Falk Hildebrand…

GMFH Editing Team
GMFH Editing Team

Scientists from Brussels University noticed recently in a recent published article that enterotypes could be found also in mice model whatever the genetic background. Although genetic and environmental factor have to be taken in account during any experiment with mice, authors also said that mice enterotypes have also to be controlled. The two first authors of this study, Falk Hildebrand…

GMFH Editing Team
GMFH Editing Team