Category : Metabolic Conditions

Taylor Soderborg is a 3rd year MD/PhD student at the University of Colorado Denver, School of Medicine, pursuing a PhD in integrative physiology: reproductive sciences track. Her thesis work is focused on the influence of maternal diet-induced obesity on development of the infant microbiome and how this may alter immune system development and later life obesity. She plans to pursue…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Taylor Soderborg is a 3rd year MD/PhD student at the University of Colorado Denver, School of Medicine, pursuing a PhD in integrative physiology: reproductive sciences track. Her thesis work is focused on the influence of maternal diet-induced obesity on development of the infant microbiome and how this may alter immune system development and later life obesity. She plans to pursue…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

In this paper, the first aim we had with Dr. Amandine Everard, was to investigate whether some key molecules involved in the innate immune system, mainly MyD88 [myeloid differentiation primary response gene 88], may contribute to the development of obesity, diabetes and low grade inflammation. This is not something novel, because we knew that MyD88 or Toll-like receptors are involved in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

In this paper, the first aim we had with Dr. Amandine Everard, was to investigate whether some key molecules involved in the innate immune system, mainly MyD88 [myeloid differentiation primary response gene 88], may contribute to the development of obesity, diabetes and low grade inflammation. This is not something novel, because we knew that MyD88 or Toll-like receptors are involved in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Neha Alang and Colleen R. Kelly recently reported that a patient who had received fecal microbiota transplantation (FMT) developed obesity (1). Although it is impossible to be sure about the role of FMT in this very case, it seems wise to exclude obese donors from FMT. This 32-year-old patient required FMT for recurrent Clostridium difficile infection (CDI). Before FMT she…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.

Neha Alang and Colleen R. Kelly recently reported that a patient who had received fecal microbiota transplantation (FMT) developed obesity (1). Although it is impossible to be sure about the role of FMT in this very case, it seems wise to exclude obese donors from FMT. This 32-year-old patient required FMT for recurrent Clostridium difficile infection (CDI). Before FMT she…

Philippe Marteau
Gastroenterologist, Head of the Medico-surgical department of Hepato-gastroenterology, Lariboisière Hospital, Paris. Professor of gastroenterology at Paris 7 University. Philippe Marteau received his PhD from the University Paris XI, France, in 1994. His main research interest is Physiopathology of the human intestinal ecosystem (intestinal microbiota in health and disease): role of the ecosystem in the development of intestinal diseases, especially inflammatory bowel diseases (Crohn’s disease, ulcerative colitis...) and irritable bowel syndrome (IBS); treatment or prevention (1st axis: description of the ecosystem in different physiological situations and pathological conditions -inflammatory bowel disease, cancers, polyps- / 2nd axis: modulation of the ecosystem using probiotics, prebiotics or other food substrates). Philippe Marteau has published >270 publications in peer reviewed scientific journals. He is member of the French Society of Gastroenterology, ECCO and of IOIBD (International Organization of Inflammatory Bowel Diseases), GETAID. He is president of the French “Collégiale des Universitaires d’Hépatogastroentérologie”. He has been principal investigator of several randomized controlled trials using drugs or probiotics in the treatment of various gastrointestinal diseases, especially inflammatory bowel disease and irritable bowel syndrome.

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

I participated to the conference "Targeting Microbiota" to update my knowledge concerning the gut microbiota and to foster collaborations with other scientists in the field. It was also a great opportunity to present my ongoing work. This congress was scientifically very fruitful. I was impressed by the quality of the invited speakers. The congress covered a broad panel of pathologies…

Laure Bindels
I am a PharmD with a PhD in Pharmaceutical Sciences. I did my PhD in nutrition and metabolism in the lab of Prof Delzenne (Université catholique de Louvain), working on the interest of gut microbiota modulation in the control of cancer progression and associated cachexia. I spent a year as a Postdoctoral Research Associate at the University of Nebraska-Lincoln (Prof Ramer-Tait and Prof Jens Walter) working on resistant starches and gut microbiota, where I acquired skills in gnotobiology and bioinformatics analysis. I am now a FNRS Postdoctoral fellow in the lab of Prof Delzenne.

In recent years, several studies reported a shift in the intestinal microbiota in humans and mice in response to high-fat diets. This shift is characterised by a reduction of Bacteroidetes and an increase of Firmicutes. The Erysipelotrichi, a bacterial class within the Firmicutes, was shown to be associated with symptoms of the metabolic syndrome. Furthermore, faecal transplantation transmitted the obese…

GMFH Editing Team
GMFH Editing Team

In recent years, several studies reported a shift in the intestinal microbiota in humans and mice in response to high-fat diets. This shift is characterised by a reduction of Bacteroidetes and an increase of Firmicutes. The Erysipelotrichi, a bacterial class within the Firmicutes, was shown to be associated with symptoms of the metabolic syndrome. Furthermore, faecal transplantation transmitted the obese…

GMFH Editing Team
GMFH Editing Team

This comprehensive set of studies, by researchers in Israel, showed that intestinal microbiota in mice and humans show diurnal changes in composition and function. The changes happen on the scale of hours, and are influenced by the host's feeding rhythms. It is already known that chronic jet lag and shift work is associated with dysbiosis. Here, researchers induced jet lag…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

This comprehensive set of studies, by researchers in Israel, showed that intestinal microbiota in mice and humans show diurnal changes in composition and function. The changes happen on the scale of hours, and are influenced by the host's feeding rhythms. It is already known that chronic jet lag and shift work is associated with dysbiosis. Here, researchers induced jet lag…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

The 2nd congress on targeting microbiota was held at Institut Pasteur in Paris on October 16-17, 2014. Professor Marvin Edeas, chairman of the scientific committee, warned the attendees about avoiding speculation where the challenge might be prevention instead of finding treatment. This should constitute a step "towards clinical revolution". To introduce this state of the art session, Pierre-Henri Gouyon, French National…

GMFH Editing Team
GMFH Editing Team

The 2nd congress on targeting microbiota was held at Institut Pasteur in Paris on October 16-17, 2014. Professor Marvin Edeas, chairman of the scientific committee, warned the attendees about avoiding speculation where the challenge might be prevention instead of finding treatment. This should constitute a step "towards clinical revolution". To introduce this state of the art session, Pierre-Henri Gouyon, French National…

GMFH Editing Team
GMFH Editing Team

Researchers from Israel recently published in Nature how NAS [Non-caloric artificial sweeteners] affect glucose tolerance. In an initial experiment, researchers found mice that consumed water, glucose, or sucrose had comparable glucose tolerance curves, but all 3 mouse groups consuming NAS (either saccharin, sucralose, or aspartame) developed marked glucose intolerance. They focused on saccharin for the next series of experiments, since…

GMFH Editing Team
GMFH Editing Team

Researchers from Israel recently published in Nature how NAS [Non-caloric artificial sweeteners] affect glucose tolerance. In an initial experiment, researchers found mice that consumed water, glucose, or sucrose had comparable glucose tolerance curves, but all 3 mouse groups consuming NAS (either saccharin, sucralose, or aspartame) developed marked glucose intolerance. They focused on saccharin for the next series of experiments, since…

GMFH Editing Team
GMFH Editing Team

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Numerous commensal bacteria present in the gut microbiota produce short chain fatty acids (SCFA’s) particularly acetate, butyrate and propionate. These SCFA’s have been associated with several biological effects upon host. Growing evidence suggests that specific microbes such as Faecalibacterium prausnitzii and Akkermansia muciniphila have favorable effects on intestinal inflammation and obesity, respectively (Sokol et al. PNAS 2008, Everard et al.…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

Karine Clément is a physician and a professor at Paris 6 Pierre et Marie Curie University in Paris and director of an INSERM team. She is also the director of ICAN (Institute of Cardiometabolism and Nutrition),Pitié-Salpêtrière hospital, which focuses on care, research, and training in cardiometabolic diseases with the aim of developing methods for personalized medicine. She recently gave a talk…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter

Karine Clément is a physician and a professor at Paris 6 Pierre et Marie Curie University in Paris and director of an INSERM team. She is also the director of ICAN (Institute of Cardiometabolism and Nutrition),Pitié-Salpêtrière hospital, which focuses on care, research, and training in cardiometabolic diseases with the aim of developing methods for personalized medicine. She recently gave a talk…

Kristina Campbell
Science writer Kristina Campbell (M.Sc.), from British Columbia (Canada), specializes in communicating about the gut microbiota, digestive health, and nutrition. Author of the best selling Well-Fed Microbiome Cookbook, her freelance work has appeared in publications around the world. Kristina joined the Gut Microbiota for Health publishing team in 2014.  Find her on: GoogleTwitter