Category : Immune Health

Dr Elena Verdú's lab seeks to understand the complex pathophysiology of gastrointestinal disease, with a focus on microbiota-diet interactions, to identify novel therapeutic targets for these disorders.     1/ What strikes you most in the evolution of research on gut microbiota and why? One interesting aspect relates to the way we have approached the study of the microbiota. We…

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GMFH Editing Team

Dr Elena Verdú's lab seeks to understand the complex pathophysiology of gastrointestinal disease, with a focus on microbiota-diet interactions, to identify novel therapeutic targets for these disorders.     1/ What strikes you most in the evolution of research on gut microbiota and why? One interesting aspect relates to the way we have approached the study of the microbiota. We…

GMFH Editing Team
GMFH Editing Team

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team

[This article is an outside contribution by Dr Patricia Lepage (INRA), co-author of the paper. For further references about the author, see the short bio hereunder]   Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (National Agronomic Research Institute) in France has led to a rather surprising discovery on the manner in which cancer…

GMFH Editing Team
GMFH Editing Team

Humans are not (and have never been) alone. From the moment we are born, millions of micro-organisms populate our bodies and coexist with us rather peacefully for the rest of our lives. This microbiome represents the totality of micro-organisms (and their genomes) that we necessarily acquire from the environment. Micro-organisms living in or on us have evolved to extract the…

GMFH Editing Team
GMFH Editing Team

Humans are not (and have never been) alone. From the moment we are born, millions of micro-organisms populate our bodies and coexist with us rather peacefully for the rest of our lives. This microbiome represents the totality of micro-organisms (and their genomes) that we necessarily acquire from the environment. Micro-organisms living in or on us have evolved to extract the…

GMFH Editing Team
GMFH Editing Team

Speakers: Anne Vrieze (Netherlands), Lawrence Brandt (USA)   Dr Vrieze’s talk focused on faecal microbiota transplantation (FMT) as a therapy for metabolic syndrome and C. difficile inflammation (CDI), under the guiding question whether the lacking diversity of the gut microbiota, which is assumed to play a major role in the disease onset, can be restored by the infusion of donor…

GMFH Editing Team
GMFH Editing Team

Speakers: Anne Vrieze (Netherlands), Lawrence Brandt (USA)   Dr Vrieze’s talk focused on faecal microbiota transplantation (FMT) as a therapy for metabolic syndrome and C. difficile inflammation (CDI), under the guiding question whether the lacking diversity of the gut microbiota, which is assumed to play a major role in the disease onset, can be restored by the infusion of donor…

GMFH Editing Team
GMFH Editing Team

Knowing how microbiota is established in the gut is a very important topic regarding epithelium maturation and immune system developpement. The early studies focused on the dynamic of the microbiota in infant aiming to understand homeostasy mecanisms. The early life microbiota show a low diversity but an high variation in term of species abundance between infants. One of the basic…

GMFH Editing Team
GMFH Editing Team

Knowing how microbiota is established in the gut is a very important topic regarding epithelium maturation and immune system developpement. The early studies focused on the dynamic of the microbiota in infant aiming to understand homeostasy mecanisms. The early life microbiota show a low diversity but an high variation in term of species abundance between infants. One of the basic…

GMFH Editing Team
GMFH Editing Team

Stool transplants highly efficient for Clostridium difficile infections and other gastrointestinal conditions — online press conference at 2nd World Summit “Gut Microbiota For Health” held today (26 February 2013) Clostridium difficile infections have developed into a virtual pandemic over the past two decades. The outcome of standard antibiotic treatment is unsatisfactory: the recurrence rates are high with every relapse increasing…

GMFH Editing Team
GMFH Editing Team

Stool transplants highly efficient for Clostridium difficile infections and other gastrointestinal conditions — online press conference at 2nd World Summit “Gut Microbiota For Health” held today (26 February 2013) Clostridium difficile infections have developed into a virtual pandemic over the past two decades. The outcome of standard antibiotic treatment is unsatisfactory: the recurrence rates are high with every relapse increasing…

GMFH Editing Team
GMFH Editing Team

The gut microbiota has an essential role in stimulating the development and maintenance of the intestinal immune system – in fact, without the gut microbiome the human body would be unable to protect its health from being affected by all environmental pathogens that enter the body, e.g. through our daily food. The cellular and molecular mechanisms by which this is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.

The gut microbiota has an essential role in stimulating the development and maintenance of the intestinal immune system – in fact, without the gut microbiome the human body would be unable to protect its health from being affected by all environmental pathogens that enter the body, e.g. through our daily food. The cellular and molecular mechanisms by which this is…

Paul Enck
Prof. Dr. Paul Enck, Director of Research, Dept. of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Germany. His main interests are gut functions in health and disease, including functional and inflammatory bowel disorders, the role of the gut microbiota, regulation of eating and food intake and its disorders, of nausea, vomiting and motion sickness, and the psychophysiology and neurobiology of the placebo response, with specific emphasis on age and gender contributions. He has published more than 170 original data paper in scientific, peer-reviewed journals, and more than 250 book chapters and review articles. He is board member/treasurer of the European Society of Neurogastroenterology and Motility and of the German Society of Neurogastroenterology and Motility, and has served as reviewer for many international journals and grant agencies.