Category : Inflammation

In this paper, the first aim we had with Dr. Amandine Everard, was to investigate whether some key molecules involved in the innate immune system, mainly MyD88 [myeloid differentiation primary response gene 88], may contribute to the development of obesity, diabetes and low grade inflammation. This is not something novel, because we knew that MyD88 or Toll-like receptors are involved in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

In this paper, the first aim we had with Dr. Amandine Everard, was to investigate whether some key molecules involved in the innate immune system, mainly MyD88 [myeloid differentiation primary response gene 88], may contribute to the development of obesity, diabetes and low grade inflammation. This is not something novel, because we knew that MyD88 or Toll-like receptors are involved in…

Patrice D. Cani
Professor Patrice D. Cani is researcher from the Belgian Fund for Scientific Research (FRS-FNRS), group leader in the Metabolism and Nutrition research group at the Louvain Drug Research Institute (LDRI) from the Université catholique de Louvain (UCL), Brussels, Belgium, and WELBIO (Walloon Excellence in Lifesciences and BIOtechnology) investigator. He is currently member of several international associations, he is member of the Alumni College from the Royal Belgian Academy of Sciences, and he has been elected in the board of directors of the LDRI (UCL). Patrice D. Cani has a M.Sc. in Nutrition and another M.Sc. in health Sciences, he is registered dietitian and PhD in Biomedical Sciences. His main research interests are the investigation of the role of the gut microbiota in the development of metabolic disorders, such as obesity, type 2 diabetes and low grade inflammation. More specifically, he is investigating the interactions between the gut microbiota, the host and specific biological systems such as the endocannabinoid system and the innate immune system in the context of obesity, type 2 diabetes and metabolic inflammation. Prof Cani is author and co-author of more than 110 scientific research papers published in peer-reviewed international journals, conferences and book chapters.

The Inflammatory Bowel Diseases (IBDs), which include Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract. The etiology of IBDs is not known yet but it is certainly multi-factorial and it includes genetic as well as environmental factors. Over the last years it has become clear, however, that IBD develops in genetically…

Marcello Romeo
Dr Marcello Romeo is currently at PHD School in Molecular and Experimental Medicine at Department of Experimental Biomedicine and Clinical Neuroscience at University of Palermo (Italy). His main research interest is the molecular assessment of the Human Intestinal Microbiota in health and disease and investigation of the molecular cross-talk between intestinal bacteria and Heat Shock Proteins in colon mucosa of Inflammatory Bowel Disease and Colon Cancer.

The Inflammatory Bowel Diseases (IBDs), which include Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract. The etiology of IBDs is not known yet but it is certainly multi-factorial and it includes genetic as well as environmental factors. Over the last years it has become clear, however, that IBD develops in genetically…

Marcello Romeo
Dr Marcello Romeo is currently at PHD School in Molecular and Experimental Medicine at Department of Experimental Biomedicine and Clinical Neuroscience at University of Palermo (Italy). His main research interest is the molecular assessment of the Human Intestinal Microbiota in health and disease and investigation of the molecular cross-talk between intestinal bacteria and Heat Shock Proteins in colon mucosa of Inflammatory Bowel Disease and Colon Cancer.

TH17 (T helper 17) has emerged as a novel potential therapeutic agent for the control of intestinal inflammatory conditions. These cells are most abundant in the small intestinal lamina propris. IL-17 (Interleukin 17A) expressing CD4+T lymphocytes (Th17) cells naturally reside in the intestine's lamina propria where specific cytokines and microbiota, such as segmented filamentous bacteria (SFB), promote the differentiation. To…

Laure Bindels
Satheesh Natarajan, Ph.D., is a postdoctoral research fellow at the Laboratory of Biomedicine and Molecular Immunology, University of Veterinary Medicine and Pharmacy, in Kosice, Slovakia. His work is in immunology and molecular biology.

TH17 (T helper 17) has emerged as a novel potential therapeutic agent for the control of intestinal inflammatory conditions. These cells are most abundant in the small intestinal lamina propris. IL-17 (Interleukin 17A) expressing CD4+T lymphocytes (Th17) cells naturally reside in the intestine's lamina propria where specific cytokines and microbiota, such as segmented filamentous bacteria (SFB), promote the differentiation. To…

Laure Bindels
Satheesh Natarajan, Ph.D., is a postdoctoral research fellow at the Laboratory of Biomedicine and Molecular Immunology, University of Veterinary Medicine and Pharmacy, in Kosice, Slovakia. His work is in immunology and molecular biology.

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team

Sahar El Aidy presented us her recent work about mice colonization as a model to study host-microbial homeostasis dynamics. This work was done under the supervision of Michiel Kleerebezem at Wageningen University (The Netherlands) : 1) What is your background ? I received my BSc degree in Pharmaceutical Sciences at the Faculty of Pharmacy, Alexandria University, Egypt, my MSc degree…

GMFH Editing Team
GMFH Editing Team